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Spyre Therapeutics

77 hedge funds and large institutions have $137M invested in Spyre Therapeutics in 2019 Q2 according to their latest regulatory filings, with 16 funds opening new positions, 35 increasing their positions, 9 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

289% more repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 9

100% more first-time investments, than exits

New positions opened: 16 | Existing positions closed: 8

8% more funds holding

Funds holding: 7177 (+6)

0.04% more ownership

Funds ownership: 2.74%2.78% (+0.04%)

14% less capital invested

Capital invested by funds: $159M → $137M (-$21.9M)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

100% less call options, than puts

Call options by funds: $0 | Put options by funds: $1K

Holders
77
Holders Change
+6
Holders Change %
+8.45%
% of All Funds
1.67%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.07%
New
16
Increased
35
Reduced
9
Closed
8
Calls
Puts
$1K
Net Calls
-$1K
Net Calls Change
-$1K
Name Holding Trade Value Shares
Change
Change in
Stake
NCM
1
Nantahala Capital Management
Connecticut
$19.5M +$1.38M +8,000 +8%
O
2
OrbiMed
New York
$14.8M
BlackRock
3
BlackRock
New York
$12.7M +$2.52M +14,573 +24%
BBA
4
Baker Bros. Advisors
New York
$11.7M
Adage Capital Partners
5
Adage Capital Partners
Massachusetts
$10.1M
ACM
6
Aisling Capital Management
New York
$8.84M +$486K +2,810 +6%
Vanguard Group
7
Vanguard Group
Pennsylvania
$7.57M -$38K -220 -0.5%
RSCM
8
Rock Springs Capital Management
Maryland
$5.48M
Marshall Wace
9
Marshall Wace
United Kingdom
$4.51M +$1.96M +11,312 +75%
Renaissance Technologies
10
Renaissance Technologies
New York
$3.73M +$631K +3,648 +20%
Dimensional Fund Advisors
11
Dimensional Fund Advisors
Texas
$3.56M +$477K +2,760 +15%
DM
12
Deerfield Management
New York
$3.42M
Goldman Sachs
13
Goldman Sachs
New York
$2.71M -$50.8K -294 -2%
State Street
14
State Street
Massachusetts
$2.63M +$963K +5,570 +57%
UOTTAIMCU
15
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$2.3M
Geode Capital Management
16
Geode Capital Management
Massachusetts
$2.05M +$403K +2,334 +24%
RWM
17
Ritholtz Wealth Management
New York
$1.99M
A
18
Abingworth
United Kingdom
$1.64M
Northern Trust
19
Northern Trust
Illinois
$1.61M +$129K +747 +9%
Assenagon Asset Management
20
Assenagon Asset Management
Luxembourg
$1.42M +$787K +4,551 +121%
FI
21
Fosun International
China
$1.31M +$194K +1,120 +16%
SFM
22
Sphera Funds Management
Israel
$1.28M -$5.45M -31,512 -81%
AG
23
Artal Group
Luxembourg
$1.16M +$1.17M +6,758 New
N
24
Nuveen
North Carolina
$951K +$960K +5,556 New
BCM
25
Bridgeway Capital Management
Texas
$702K

SYRE Hedge Fund Activity: Q2 2019 in Review

77 of the 4,605 institutional investors tracked by Wall St. Rank reported a position in Spyre Therapeutics (SYRE) for Q2 2019, worth a combined $137M — down 14% from $159M a quarter earlier.

Buyers outnumbered sellers: 16 funds opened new SYRE positions and 8 closed out — a net gain of 8 holders — while 35 added to existing stakes and 9 trimmed.

The largest buyer was BlackRock, adding an estimated $2.52M. The largest seller was Jennison Associates, exiting entirely with an estimated $6.25M sold.

  • 77 institutional investors held Spyre Therapeutics (SYRE) as of Q2 2019, up from 71 in Q1 2019.
  • Funds reported $137M of Spyre Therapeutics stock for Q2 2019, down 14% quarter-over-quarter.
  • 16 funds opened new Spyre Therapeutics positions in Q2 2019 and 8 closed out, a net change of +8 holders.
  • The largest Spyre Therapeutics buyer in Q2 2019 was BlackRock, an estimated $2.52M added.
  • The largest Spyre Therapeutics seller in Q2 2019 was Jennison Associates, an estimated $6.25M sold.

Based on aggregated 13F filings for Q2 2019.