|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$1.16B
|
+$90.9M
|
+1,245,163
|
+11%
|
|
|
2
|
|
$578M
|
+$71.9M
|
+985,384
|
+18%
|
|
|
3
|
Perceptive Advisors
New York
|
$383M
|
+$39.1M
|
+536,271
|
+14%
|
|
|
4
|
|
$377M
|
+$5.84M
|
+80,000
|
+2%
|
|
|
5
|
Paradigm Biocapital Advisors
New York
|
$341M
|
+$137M
|
+1,883,512
|
+96%
|
|
|
6
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$306M
|
+$28.6M
|
+391,280
|
+13%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$271M
|
+$32.9M
|
+450,385
|
+17%
|
|
|
8
|
|
$265M
|
-$51.1M
|
-700,000
|
-19%
|
|
|
9
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$263M
|
+$99.4M
|
+1,362,125
|
+85%
|
|
|
10
|
Driehaus Capital Management
Chicago,
Illinois
|
$249M
|
+$612K
|
+8,381
|
+0.3%
|
|
|
11
|
Geode Capital Management
Boston,
Massachusetts
|
$239M
|
+$61.4M
|
+841,353
|
+49%
|
|
|
12
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$207M
|
+$127M
|
+1,744,968
|
+298%
|
|
|
13
|
Capital World Investors
Los Angeles,
California
|
$206M
|
+$120M
|
+1,648,989
|
+247%
|
|
|
14
|
|
$196M
|
+$161M
|
+2,206,936
|
New
|
|
|
15
|
TCG Crossover Management
Palo Alto,
California
|
$169M
|
–
|
–
|
–
|
|
|
16
|
Tang Capital Management
San Diego,
California
|
$168M
|
–
|
–
|
–
|
|
|
17
|
Bank of America
Charlotte,
North Carolina
|
$158M
|
+$40.1M
|
+549,761
|
+45%
|
|
|
18
|
Adage Capital Partners
Boston,
Massachusetts
|
$153M
|
+$126M
|
+1,722,300
|
New
|
|
|
19
|
Wellington Management Group
Boston,
Massachusetts
|
$140M
|
-$17.8M
|
-243,306
|
-13%
|
|
|
20
|
|
$131M
|
+$88.2M
|
+1,208,121
|
+448%
|
|
|
21
|
Franklin Resources
San Mateo,
California
|
$131M
|
+$43.1M
|
+590,110
|
+67%
|
|
|
22
|
Remedium Capital Partners
Fort Lauderdale,
Florida
|
$130M
|
+$579K
|
+7,938
|
+0.5%
|
|
|
23
|
Affinity Asset Advisors
New York
|
$114M
|
–
|
–
|
–
|
|
|
24
|
|
$98.9M
|
+$8.3M
|
+113,727
|
+12%
|
|
|
25
|
Holocene Advisors
New York
|
$90.1M
|
+$74.1M
|
+1,015,170
|
New
|
|
