JP Morgan Chase’s Spyre Therapeutics SYRE Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2026
Q2
$98.9M Buy
1,093,026
+113,727
+12% +$8.3M 0.01% 1078
2026
Q1
$44.5M Buy
979,299
+916,348
+1,456% +$34.5M ﹤0.01% 1467
2025
Q4
$2.06M Sell
62,951
-213,033
-77% -$5.57M ﹤0.01% 4046
2025
Q3
$4.63M Buy
275,984
+228,705
+484% +$3.73M ﹤0.01% 3438
2025
Q2
$708K Buy
47,279
+5,723
+14% +$84.7K ﹤0.01% 4592
2025
Q1
$671K Buy
41,556
+6,308
+18% +$131K ﹤0.01% 4593
2024
Q4
$821K Buy
35,248
+5,775
+20% +$169K ﹤0.01% 4762
2024
Q3
$867K Buy
29,473
+6,701
+29% +$187K ﹤0.01% 4555
2024
Q2
$535K Buy
22,772
+22,761
+206,918% +$768K ﹤0.01% 4657
2024
Q1
$417 Sell
11
-30
-73% -$869 ﹤0.01% 6743
2023
Q4
$882 Hold
41
﹤0.01% 6851
2023
Q3
$502 Sell
41
-2
-5% -$26 ﹤0.01% 6728
2023
Q2
$481 Hold
43
﹤0.01% 6551
2023
Q1
$0 Hold
43
﹤0.01% 7208
2022
Q4
$0 Sell
43
-103
-71% -$1.85K ﹤0.01% 6985
2022
Q3
$2K Buy
146
+53
+57% +$655 ﹤0.01% 6266
2022
Q2
$1K Sell
93
-904
-91% -$31.7K ﹤0.01% 6382
2022
Q1
$58K Buy
997
+162
+19% +$13.6K ﹤0.01% 5739
2021
Q4
$99K Buy
835
+68
+9% +$10.7K ﹤0.01% 5688
2021
Q3
$152K Sell
767
-2,738
-78% -$479K ﹤0.01% 5367
2021
Q2
$610K Buy
3,505
+2,345
+202% +$426K ﹤0.01% 4575
2021
Q1
$230K Sell
1,160
-24
-2% -$4.61K ﹤0.01% 5092
2020
Q4
$233K Buy
1,184
+558
+89% +$116K ﹤0.01% 4758
2020
Q3
$111K Buy
626
+61
+11% +$11.3K ﹤0.01% 4643
2020
Q2
$131K Sell
565
-743
-57% -$142K ﹤0.01% 4457
2020
Q1
$152K Sell
1,308
-630
-33% -$107K ﹤0.01% 4381
2019
Q4
$371K Sell
1,938
-256
-12% -$50.2K ﹤0.01% 4385
2019
Q3
$422K Buy
2,194
+56
+3% +$10.9K ﹤0.01% 4246
2019
Q2
$343K Buy
2,138
+1,871
+701% +$323K ﹤0.01% 4411
2019
Q1
$53K Buy
267
+99
+59% +$20.6K ﹤0.01% 5109
2018
Q4
$32K Sell
168
-1,660
-91% -$352K ﹤0.01% 5222
2018
Q3
$437K Sell
1,828
-2,973
-62% -$694K ﹤0.01% 4339
2018
Q2
$1.27M Buy
4,801
+2,775
+137% +$683K ﹤0.01% 3691
2018
Q1
$502K Buy
2,026
+1,784
+737% +$322K ﹤0.01% 4010
2017
Q4
$33K Buy
242
+234
+2,925% +$28.6K ﹤0.01% 5030
2017
Q3
$1K Sell
8
-43
-84% -$4.03K ﹤0.01% 4914
2017
Q2
$5K Buy
+51
New +$7.05K ﹤0.01% 4761

Other funds holding SYRE

JP Morgan Chase's SYRE Position: Q2 2026 in Review

JP Morgan Chase increased its Spyre Therapeutics (SYRE) stake by 12% in Q2 2026, buying an estimated $8.3M and bringing the position to 1,093,026 shares worth $98.9M. The position accounts for 0.01% of the portfolio, ranked #1078.

JP Morgan Chase first reported a position in SYRE in Q2 2017 and has held it in 37 quarters since. 265 funds tracked by Wall St. Rank hold SYRE as of Q2 2026.

  • JP Morgan Chase held 1,093,026 shares of Spyre Therapeutics worth $98.9M as of Q2 2026.
  • JP Morgan Chase bought 113,727 Spyre Therapeutics shares in Q2 2026, an estimated $8.3M.
  • Spyre Therapeutics made up 0.01% of JP Morgan Chase's portfolio in Q2 2026, its #1078 holding.
  • JP Morgan Chase first reported a position in Spyre Therapeutics in Q2 2017 and has held it in 37 quarters since.
  • 265 funds tracked by Wall St. Rank held Spyre Therapeutics as of Q2 2026.

Based on JP Morgan Chase's 13F filing for Q2 2026, filed 12 Aug 2026.