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Spyre Therapeutics

71 hedge funds and large institutions have $154M invested in Spyre Therapeutics in 2019 Q3 according to their latest regulatory filings, with 6 funds opening new positions, 24 increasing their positions, 22 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,800% more call options, than puts

Call options by funds: $19K | Put options by funds: $1K

13% more capital invested

Capital invested by funds: $137M → $154M (+$17.4M)

9% more repeat investments, than reductions

Existing positions increased: 24 | Existing positions reduced: 22

0% more ownership

Funds ownership: 2.78%2.78% (+0%)

8% less funds holding

Funds holding: 7771 (-6)

33% less funds holding in top 10

Funds holding in top 10: 32 (-1)

45% less first-time investments, than exits

New positions opened: 6 | Existing positions closed: 11

Holders
71
Holders Change
-6
Holders Change %
-7.79%
% of All Funds
1.56%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.04%
New
6
Increased
24
Reduced
22
Closed
11
Calls
$19K
Puts
$1K
Net Calls
+$18K
Net Calls Change
+$19K
Name Holding Trade Value Shares
Change
Change in
Stake
O
1
OrbiMed
New York
$22M +$5.45M +28,000 +32%
NCM
2
Nantahala Capital Management
Connecticut
$21.9M
BlackRock
3
BlackRock
New York
$14.6M +$372K +1,912 +3%
BBA
4
Baker Bros. Advisors
New York
$13.2M
Adage Capital Partners
5
Adage Capital Partners
Massachusetts
$11.3M
ACM
6
Aisling Capital Management
New York
$9.93M
Vanguard Group
7
Vanguard Group
Pennsylvania
$8.68M +$191K +982 +2%
Marshall Wace
8
Marshall Wace
United Kingdom
$6.16M +$1.11M +5,676 +22%
RSCM
9
Rock Springs Capital Management
Maryland
$6.15M
Renaissance Technologies
10
Renaissance Technologies
New York
$4.31M +$122K +628 +3%
Dimensional Fund Advisors
11
Dimensional Fund Advisors
Texas
$4.12M +$127K +654 +3%
DM
12
Deerfield Management
New York
$3.85M
Goldman Sachs
13
Goldman Sachs
New York
$3.35M +$303K +1,557 +10%
State Street
14
State Street
Massachusetts
$3.32M +$369K +1,897 +12%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$2.4M +$104K +536 +4%
Northern Trust
16
Northern Trust
Illinois
$2.32M +$527K +2,704 +29%
AG
17
Artal Group
Luxembourg
$2.31M +$1.02M +5,242 +78%
RWM
18
Ritholtz Wealth Management
New York
$2.04M -$202K -1,035 -9%
A
19
Abingworth
United Kingdom
$1.85M
Russell Investments Group
20
Russell Investments Group
United Kingdom
$1.17M +$1.18M +6,078 +37,988%
N
21
Nuveen
North Carolina
$1.06M -$6.82K -35 -0.6%
BCM
22
Bridgeway Capital Management
Texas
$788K
Bank of New York Mellon
23
Bank of New York Mellon
New York
$690K -$46.2K -237 -6%
Squarepoint
24
Squarepoint
New York
$545K +$140K +719 +34%
Charles Schwab
25
Charles Schwab
California
$459K

SYRE Hedge Fund Activity: Q3 2019 in Review

71 of the 4,561 institutional investors tracked by Wall St. Rank reported a position in Spyre Therapeutics (SYRE) for Q3 2019, worth a combined $154M — up 13% from $137M a quarter earlier.

Sellers outnumbered buyers: 11 funds closed out of SYRE and 6 opened new positions — a net loss of 5 holders — while 22 trimmed existing stakes and 24 added.

The largest buyer was OrbiMed, adding an estimated $5.45M. The largest seller was Assenagon Asset Management, cutting an estimated $1.52M.

  • 71 institutional investors held Spyre Therapeutics (SYRE) as of Q3 2019, down from 77 in Q2 2019.
  • Funds reported $154M of Spyre Therapeutics stock for Q3 2019, up 13% quarter-over-quarter.
  • 6 funds opened new Spyre Therapeutics positions in Q3 2019 and 11 closed out, a net change of -5 holders.
  • The largest Spyre Therapeutics buyer in Q3 2019 was OrbiMed, an estimated $5.45M added.
  • The largest Spyre Therapeutics seller in Q3 2019 was Assenagon Asset Management, an estimated $1.52M sold.

Based on aggregated 13F filings for Q3 2019.