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Spyre Therapeutics

71 hedge funds and large institutions have $154M invested in Spyre Therapeutics in 2019 Q3 according to their latest regulatory filings, with 6 funds opening new positions, 24 increasing their positions, 22 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
71
Holders Change
-6
Holders Change %
-7.79%
% of All Funds
1.56%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.04%
New
6
Increased
24
Reduced
22
Closed
11
Calls
$19K
Puts
$1K
Net Calls
+$18K
Net Calls Change
+$19K
Name Holding Trade Value Shares
Change
Shares
Change %
O
1
OrbiMed
New York
$22M +$5.38M +28,000 +32%
NCM
2
Nantahala Capital Management
Connecticut
$21.9M
BlackRock
3
BlackRock
New York
$14.6M +$368K +1,912 +3%
BBA
4
Baker Bros. Advisors
New York
$13.2M
Adage Capital Partners
5
Adage Capital Partners
Massachusetts
$11.3M
ACM
6
Aisling Capital Management
New York
$9.93M
Vanguard Group
7
Vanguard Group
Pennsylvania
$8.68M +$189K +982 +2%
Marshall Wace
8
Marshall Wace
United Kingdom
$6.16M +$1.09M +5,676 +22%
RSCM
9
Rock Springs Capital Management
Maryland
$6.15M
Renaissance Technologies
10
Renaissance Technologies
New York
$4.31M +$121K +628 +3%
Dimensional Fund Advisors
11
Dimensional Fund Advisors
Texas
$4.12M +$126K +654 +3%
DM
12
Deerfield Management
New York
$3.85M
Goldman Sachs
13
Goldman Sachs
New York
$3.35M +$299K +1,557 +10%
State Street
14
State Street
Massachusetts
$3.32M +$365K +1,897 +12%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$2.4M +$103K +536 +4%
Northern Trust
16
Northern Trust
Illinois
$2.32M +$520K +2,704 +29%
AG
17
Artal Group
Luxembourg
$2.31M +$1.01M +5,242 +78%
RWM
18
Ritholtz Wealth Management
New York
$2.04M -$199K -1,035 -9%
A
19
Abingworth
United Kingdom
$1.85M
Russell Investments Group
20
Russell Investments Group
United Kingdom
$1.17M +$1.17M +6,078 +37,988%
Nuveen Asset Management
21
Nuveen Asset Management
Illinois
$1.06M -$6.73K -35 -0.6%
BCM
22
Bridgeway Capital Management
Texas
$788K
Bank of New York Mellon
23
Bank of New York Mellon
New York
$690K -$45.6K -237 -6%
Squarepoint
24
Squarepoint
New York
$545K +$138K +719 +34%
Charles Schwab
25
Charles Schwab
California
$459K