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Spyre Therapeutics

23 hedge funds and large institutions have $38.5M invested in Spyre Therapeutics in 2017 Q1 according to their latest regulatory filings, with 7 funds opening new positions, 5 increasing their positions, 5 reducing their positions, and 7 closing their positions.

New
Increased
Maintained
Reduced
Closed

58% more capital invested

Capital invested by funds: $24.4M → $38.5M (+$14.1M)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

0% more first-time investments, than exits

New positions opened: 7 | Existing positions closed: 7

0% more repeat investments, than reductions

Existing positions increased: 5 | Existing positions reduced: 5

0.13% less ownership

Funds ownership: 1.67%1.54% (-0.13%)

12% less funds holding

Funds holding: 2623 (-3)

Holders
23
Holders Change
-3
Holders Change %
-11.54%
% of All Funds
0.57%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.02%
New
7
Increased
5
Reduced
5
Closed
7
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
O
1
OrbiMed
New York
$10.9M +$617K +4,372 +8%
Jennison Associates
2
Jennison Associates
New York
$10.8M +$49.7K +352 +0.6%
UOTTAIMCU
3
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$3.91M
RSCM
4
Rock Springs Capital Management
Maryland
$3.9M
DCM
5
DAFNA Capital Management
California
$2.61M
BBA
6
Baker Bros. Advisors
New York
$1.42M -$1.21M -8,570 -53%
SCM
7
Sio Capital Management
New York
$1.27M -$105K -743 -10%
Vanguard Group
8
Vanguard Group
Pennsylvania
$1.03M +$468K +3,314 +151%
Alyeska Investment Group
9
Alyeska Investment Group
Illinois
$881K -$7.76K -55 -1%
NI
10
Numeric Investors
Massachusetts
$294K +$223K +1,580 New
Renaissance Technologies
11
Renaissance Technologies
New York
$270K +$204K +1,448 New
Geode Capital Management
12
Geode Capital Management
Massachusetts
$246K +$55.6K +394 +42%
LF
13
Lee Financial
Texas
$167K
Bank of New York Mellon
14
Bank of New York Mellon
New York
$157K +$119K +842 New
Northern Trust
15
Northern Trust
Illinois
$123K +$93.2K +660 New
Wells Fargo
16
Wells Fargo
California
$117K -$8.89K -63 -9%
BlackRock
17
BlackRock
New York
$113K +$85.6K +606 New
Squarepoint
18
Squarepoint
New York
$91K +$68.9K +488 New
PA
19
Perceptive Advisors
New York
$43K -$552K -3,910 -94%
Deutsche Bank
20
Deutsche Bank
Germany
$36K +$28K +198 New
IA
21
IFP Advisors
Florida
$21K
Morgan Stanley
22
Morgan Stanley
New York
$20K
UBS Group
23
UBS Group
Switzerland
$7K +$988 +7 +22%
VMI
24
VHCP Management II
New York
-$1.52M -14,005 Closed
Norges Bank
25
Norges Bank
Norway
-$275K -2,528 Closed

SYRE Hedge Fund Activity: Q1 2017 in Review

23 of the 4,018 institutional investors tracked by Wall St. Rank reported a position in Spyre Therapeutics (SYRE) for Q1 2017, worth a combined $38.5M — up 58% from $24.4M a quarter earlier.

Fund positioning in SYRE was balanced in Q1 2017: 7 funds opened new positions, 7 closed out, 5 added to existing stakes and 5 trimmed.

The largest buyer was OrbiMed, adding an estimated $617K. The largest seller was VHCP Management II, exiting entirely with an estimated $1.52M sold.

  • 23 institutional investors held Spyre Therapeutics (SYRE) as of Q1 2017, down from 26 in Q4 2016.
  • Funds reported $38.5M of Spyre Therapeutics stock for Q1 2017, up 58% quarter-over-quarter.
  • 7 funds opened new Spyre Therapeutics positions in Q1 2017 and 7 closed out, a net change of 0 holders.
  • The largest Spyre Therapeutics buyer in Q1 2017 was OrbiMed, an estimated $617K added.
  • The largest Spyre Therapeutics seller in Q1 2017 was VHCP Management II, an estimated $1.52M sold.

Based on aggregated 13F filings for Q1 2017.