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Spyre Therapeutics

26 hedge funds and large institutions have $24.4M invested in Spyre Therapeutics in 2016 Q4 according to their latest regulatory filings, with 4 funds opening new positions, 7 increasing their positions, 4 reducing their positions, and 6 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more repeat investments, than reductions

Existing positions increased: 7 | Existing positions reduced: 4

1.67% more ownership

Funds ownership: 0%1.67% (+1.7%)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

7% less funds holding

Funds holding: 2826 (-2)

33% less first-time investments, than exits

New positions opened: 4 | Existing positions closed: 6

36% less capital invested

Capital invested by funds: $38M → $24.4M (-$13.6M)

Holders
26
Holders Change
-2
Holders Change %
-7.14%
% of All Funds
0.65%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
4
Increased
7
Reduced
4
Closed
6
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
Jennison Associates
1
Jennison Associates
New York
$6.29M +$121K +831 +1%
O
2
OrbiMed
New York
$5.92M
UOTTAIMCU
3
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$2.28M
RSCM
4
Rock Springs Capital Management
Maryland
$2.28M
BBA
5
Baker Bros. Advisors
New York
$1.76M
DCM
6
DAFNA Capital Management
California
$1.52M
VMI
7
VHCP Management II
New York
$1.52M
SCM
8
Sio Capital Management
New York
$820K +$199K +1,366 +22%
Alyeska Investment Group
9
Alyeska Investment Group
Illinois
$521K +$58.6K +402 +9%
PA
10
Perceptive Advisors
New York
$451K
Norges Bank
11
Norges Bank
Norway
$275K
Vanguard Group
12
Vanguard Group
Pennsylvania
$239K +$235K +1,613 +276%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$101K +$23.8K +163 +21%
LF
14
Lee Financial
Texas
$97K +$131K +896 New
Wells Fargo
15
Wells Fargo
California
$75K +$84.4K +579 +517%
BFA
16
BlackRock Fund Advisors
California
$60K +$3.79K +26 +5%
SIM
17
Spark Investment Management
New York
$52K +$70K +480 New
Goldman Sachs
18
Goldman Sachs
New York
$45K -$132K -906 -69%
VM
19
VHCP Management
New York
$26K
Morgan Stanley
20
Morgan Stanley
New York
$12K -$6.27K -43 -28%
IA
21
IFP Advisors
Florida
$12K
BIM
22
BlackRock Investment Management
Delaware
$4K
UBS Group
23
UBS Group
Switzerland
$3K -$96.7K -663 -95%
Acadian Asset Management
24
Acadian Asset Management
Massachusetts
$2K +$2.77K +19 New
TRCT
25
Tower Research Capital (TRC)
New York
$1K -$2.92K -20 -71%

SYRE Hedge Fund Activity: Q4 2016 in Review

26 of the 4,000 institutional investors tracked by Wall St. Rank reported a position in Spyre Therapeutics (SYRE) for Q4 2016, worth a combined $24.4M — down 36% from $38M a quarter earlier.

Sellers outnumbered buyers: 6 funds closed out of SYRE and 4 opened new positions — a net loss of 2 holders — while 4 trimmed existing stakes and 7 added.

The largest buyer was Vanguard Group, adding an estimated $235K. The largest seller was RA Capital Management, exiting entirely with an estimated $2.15M sold.

  • 26 institutional investors held Spyre Therapeutics (SYRE) as of Q4 2016, down from 28 in Q3 2016.
  • Funds reported $24.4M of Spyre Therapeutics stock for Q4 2016, down 36% quarter-over-quarter.
  • 4 funds opened new Spyre Therapeutics positions in Q4 2016 and 6 closed out, a net change of -2 holders.
  • The largest Spyre Therapeutics buyer in Q4 2016 was Vanguard Group, an estimated $235K added.
  • The largest Spyre Therapeutics seller in Q4 2016 was RA Capital Management, an estimated $2.15M sold.

Based on aggregated 13F filings for Q4 2016.