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Spyre Therapeutics

33 hedge funds and large institutions have $30.4M invested in Spyre Therapeutics in 2017 Q2 according to their latest regulatory filings, with 12 funds opening new positions, 6 increasing their positions, 8 reducing their positions, and 2 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
33
Holders Change
+10
Holders Change %
+43.48%
% of All Funds
0.82%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.02%
New
12
Increased
6
Reduced
8
Closed
2
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Shares
Change %
NCM
1
Nantahala Capital Management
Connecticut
$6.13M +$6.13M +63,716 New
O
2
OrbiMed
New York
$5.66M
Jennison Associates
3
Jennison Associates
New York
$5.36M -$222K -2,314 -4%
BBA
4
Baker Bros. Advisors
New York
$4.38M +$3.65M +37,916 +499%
UOTTAIMCU
5
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$2.02M
RSCM
6
Rock Springs Capital Management
Maryland
$2.01M
DCM
7
DAFNA Capital Management
California
$1.35M -$3.08K -32 -0.2%
Susquehanna International Group
8
Susquehanna International Group
Pennsylvania
$653K +$653K +6,800 New
Vanguard Group
9
Vanguard Group
Pennsylvania
$579K +$49.8K +519 +9%
SCM
10
Sio Capital Management
New York
$499K -$155K -1,613 -24%
Alyeska Investment Group
11
Alyeska Investment Group
Illinois
$442K -$13.5K -140 -3%
BCM
12
Bridgeway Capital Management
Texas
$384K +$384K +4,000 New
NI
13
Numeric Investors
Massachusetts
$152K
Geode Capital Management
14
Geode Capital Management
Massachusetts
$117K -$9.54K -100 -8%
Renaissance Technologies
15
Renaissance Technologies
New York
$97K -$42.3K -440 -30%
LF
16
Lee Financial
Texas
$86K
Wells Fargo
17
Wells Fargo
California
$85K +$24.8K +258 +41%
BlackRock
18
BlackRock
New York
$72K +$14.1K +147 +24%
Northern Trust
19
Northern Trust
Illinois
$64K
PAM
20
Panagora Asset Management
Massachusetts
$57K +$57K +593 New
SIM
21
Spark Investment Management
New York
$54K +$54K +568 New
Bank of New York Mellon
22
Bank of New York Mellon
New York
$51K -$30K -312 -37%
OAM
23
Oxford Asset Management
United Kingdom
$48K +$48K +496 New
William Blair & Company
24
William Blair & Company
Illinois
$43K +$43K +448 New
IA
25
IFP Advisors
Florida
$11K