We are live on ! Find out more
SYRE icon

Spyre Therapeutics

31 hedge funds and large institutions have $42.9M invested in Spyre Therapeutics in 2017 Q4 according to their latest regulatory filings, with 4 funds opening new positions, 11 increasing their positions, 3 reducing their positions, and 5 closing their positions.

New
Increased
Maintained
Reduced
Closed

267% more repeat investments, than reductions

Existing positions increased: 11 | Existing positions reduced: 3

12% more capital invested

Capital invested by funds: $38.1M → $42.9M (+$4.74M)

0.01% more ownership

Funds ownership: 1.9%1.91% (+0.01%)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

3% less funds holding

Funds holding: 3231 (-1)

20% less first-time investments, than exits

New positions opened: 4 | Existing positions closed: 5

Holders
31
Holders Change
-1
Holders Change %
-3.13%
% of All Funds
0.7%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.02%
New
4
Increased
11
Reduced
3
Closed
5
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
NCM
1
Nantahala Capital Management
Connecticut
$9.98M +$1.18M +9,671 +15%
O
2
OrbiMed
New York
$7.95M
Jennison Associates
3
Jennison Associates
New York
$7.54M +$41K +335 +0.6%
BBA
4
Baker Bros. Advisors
New York
$6.16M
UOTTAIMCU
5
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$2.84M
RSCM
6
Rock Springs Capital Management
Maryland
$2.83M
DCM
7
DAFNA Capital Management
California
$1.89M
Vanguard Group
8
Vanguard Group
Pennsylvania
$1.47M +$543K +4,435 +69%
BCM
9
Bridgeway Capital Management
Texas
$541K
Dimensional Fund Advisors
10
Dimensional Fund Advisors
Texas
$196K +$111K +907 +168%
Renaissance Technologies
11
Renaissance Technologies
New York
$174K +$94.4K +772 +151%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$165K
Wells Fargo
13
Wells Fargo
California
$124K +$21.5K +176 +24%
LF
14
Lee Financial
Texas
$121K
BlackRock
15
BlackRock
New York
$119K +$17.2K +141 +19%
Northern Trust
16
Northern Trust
Illinois
$89K
PAM
17
Panagora Asset Management
Massachusetts
$86K +$18.5K +151 +31%
Jacobs Levy Equity Management
18
Jacobs Levy Equity Management
New Jersey
$85K +$76.8K +628 New
Millennium Management
19
Millennium Management
New York
$75K +$67.7K +553 New
Bank of New York Mellon
20
Bank of New York Mellon
New York
$72K
DS
21
DRW Securities
Illinois
$70K +$63K +515 New
William Blair & Company
22
William Blair & Company
Illinois
$61K
SIM
23
Spark Investment Management
New York
$60K -$151K -1,232 -73%
Acadian Asset Management
24
Acadian Asset Management
Massachusetts
$54K +$27K +221 +121%
Bank of America
25
Bank of America
North Carolina
$38K

SYRE Hedge Fund Activity: Q4 2017 in Review

31 of the 4,410 institutional investors tracked by Wall St. Rank reported a position in Spyre Therapeutics (SYRE) for Q4 2017, worth a combined $42.9M — up 12% from $38.1M a quarter earlier.

Sellers outnumbered buyers: 5 funds closed out of SYRE and 4 opened new positions — a net loss of 1 holder — while 3 trimmed existing stakes and 11 added.

The largest buyer was Nantahala Capital Management, adding an estimated $1.18M. The largest seller was Sio Capital Management, exiting entirely with an estimated $639K sold.

  • 31 institutional investors held Spyre Therapeutics (SYRE) as of Q4 2017, down from 32 in Q3 2017.
  • Funds reported $42.9M of Spyre Therapeutics stock for Q4 2017, up 12% quarter-over-quarter.
  • 4 funds opened new Spyre Therapeutics positions in Q4 2017 and 5 closed out, a net change of -1 holder.
  • The largest Spyre Therapeutics buyer in Q4 2017 was Nantahala Capital Management, an estimated $1.18M added.
  • The largest Spyre Therapeutics seller in Q4 2017 was Sio Capital Management, an estimated $639K sold.

Based on aggregated 13F filings for Q4 2017.