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Spyre Therapeutics
SYRE

Overview Fund Activity

28 hedge funds and large institutions have $38M invested in Spyre Therapeutics in 2016 Q3 according to their latest regulatory filings, with 7 funds opening new positions, 6 increasing their positions, 7 reducing their positions, and 2 closing their positions.

Holders
28
Holders Change
+5
Holders Change %
+21.74%
% of All Funds
0.75%
Holding in Top 10
1
Holding in Top 10 Change
+1
Holding in Top 10 Change %
%
% of All Funds
0.03%
New
7
Increased
6
Reduced
7
Closed
2
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
UOTTAIMCU
1
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$3.37M
2
Jennison Associates
2
Jennison Associates
New York
$9.13M
3
Geode Capital Management
3
Geode Capital Management
Massachusetts
$123K
4
Vanguard Group
4
Vanguard Group
Pennsylvania
$94K
5
SCM
5
Sio Capital Management
New York
$989K

Top Sellers

1
RCM
1
RA Capital Management
Massachusetts
$2.16M
2
Millennium Management
2
Millennium Management
New York
$230K
3
Goldman Sachs
3
Goldman Sachs
New York
$212K
4
Citadel Advisors
4
Citadel Advisors
Florida
$0
5
Norges Bank
5
Norges Bank
Norway
$387K
Name Market Value Shares Shares
Change 		Shares
Change %
Jennison Associates
1
Jennison Associates
New York
$9.13M 1,424,947 +36,868 +3%
O
2
OrbiMed
New York
$8.72M 1,360,224 – –
UOTTAIMCU
3
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$3.37M 524,929 +524,929 New
RSCM
4
Rock Springs Capital Management
Maryland
$3.36M 524,089 – –
BBA
5
Baker Bros. Advisors
New York
$2.59M 404,230 – –
DCM
6
DAFNA Capital Management
California
$2.25M 350,392 – –
VMI
7
VHCP Management II
New York
$2.24M 350,133 – –
RCM
8
RA Capital Management
Massachusetts
$2.16M 336,134 -185,416 -36%
SCM
9
Sio Capital Management
New York
$989K 154,332 +12,458 +9%
Alyeska Investment Group
10
Alyeska Investment Group
Illinois
$703K 109,645 +9,645 +10%
PA
11
Perceptive Advisors
New York
$664K 103,585 -2,308 -2%
Norges Bank
12
Norges Bank
Norway
$387K 63,200 -6,800 -10%
GTC
13
Ghost Tree Capital
New York
$321K 50,000 – –
Millennium Management
14
Millennium Management
New York
$230K 35,955 -26,699 -43%
Goldman Sachs
15
Goldman Sachs
New York
$212K 33,026 -23,208 -41%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$123K 19,219 +19,219 New
UBS Group
17
UBS Group
Switzerland
$112K 17,371 +10,171 +141%
Vanguard Group
18
Vanguard Group
Pennsylvania
$94K 14,636 +14,636 New
BFA
19
BlackRock Fund Advisors
California
$84K 13,160 +2,125 +19%
TG
20
TLP Group
Illinois
$76K 11,913 +11,913 New
CS
21
Credit Suisse
Switzerland
$64K 10,000 +10,000 New
VM
22
VHCP Management
New York
$38K 6,000 – –
Morgan Stanley
23
Morgan Stanley
New York
$25K 3,790 +3,790 New
Wells Fargo
24
Wells Fargo
California
$18K 2,800 +500 +22%
IA
25
IFP Advisors
Florida
$18K 2,860 +2,860 New
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