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Spyre Therapeutics
SYRE

Overview Fund Activity

87 hedge funds and large institutions have $352M invested in Spyre Therapeutics in 2020 Q2 according to their latest regulatory filings, with 25 funds opening new positions, 43 increasing their positions, 13 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
87
Holders Change
+17
Holders Change %
+24.29%
% of All Funds
1.79%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.06%
New
25
Increased
43
Reduced
13
Closed
8
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
BCLSI
Bain Capital Life Sciences Investors
Massachusetts
+$25M
2
BBA
Baker Bros. Advisors
New York
+$24.7M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$13.2M
4
BlackRock
BlackRock
New York
+$12.1M
5
O
OrbiMed
New York
+$10.6M

Top Sellers

1
SCM
Soleus Capital Management
Connecticut
-$1.54M
2
BCM
Bridgeway Capital Management
Texas
-$534K
3
RWM
Ritholtz Wealth Management
New York
-$462K
4
Renaissance Technologies
Renaissance Technologies
New York
-$422K
5
UOTTAIMCU
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
-$398K
Name Holding Trade Value Shares
Change 		Shares
Change %
BBA
1
Baker Bros. Advisors
New York
$40.5M +$24.7M +106,640 +156%
O
2
OrbiMed
New York
$37.1M +$10.6M +46,000 +40%
BlackRock
3
BlackRock
New York
$29.8M +$12.1M +52,314 +69%
NCM
4
Nantahala Capital Management
Connecticut
$29.6M +$3.26M +14,103 +12%
Adage Capital Partners
5
Adage Capital Partners
Massachusetts
$26.8M +$13.2M +56,936 +97%
BCLSI
6
Bain Capital Life Sciences Investors
Massachusetts
$25M +$25M +108,000 New
Vanguard Group
7
Vanguard Group
Pennsylvania
$17.1M +$6.12M +26,448 +56%
ACM
8
Aisling Capital Management
New York
$15.6M +$3.7M +16,000 +31%
RSCM
9
Rock Springs Capital Management
Maryland
$14.7M +$7.31M +31,621 +99%
Marshall Wace
10
Marshall Wace
United Kingdom
$11.6M +$3.79M +16,391 +49%
AG
11
Artal Group
Luxembourg
$10.2M +$6.48M +28,000 +175%
SB
12
Samsara BioCapital
California
$8.95M +$8.95M +38,700 New
DM
13
Deerfield Management
New York
$7.63M +$7.63M +33,000 New
State Street
14
State Street
Massachusetts
$6.04M +$1.68M +7,244 +38%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$5.39M +$2.44M +10,543 +83%
Renaissance Technologies
16
Renaissance Technologies
New York
$5.13M -$422K -1,824 -8%
BC
17
Boxer Capital
California
$5.09M +$5.09M +22,000 New
Northern Trust
18
Northern Trust
Illinois
$4.62M +$1.87M +8,106 +68%
Dimensional Fund Advisors
19
Dimensional Fund Advisors
Texas
$4.61M -$269K -1,164 -6%
Goldman Sachs
20
Goldman Sachs
New York
$4.21M +$307K +1,326 +8%
DCM
21
Driehaus Capital Management
Illinois
$3.98M +$3.98M +17,188 New
SCM
22
Soleus Capital Management
Connecticut
$3.42M -$1.54M -6,666 -31%
Assenagon Asset Management
23
Assenagon Asset Management
Luxembourg
$3.08M +$3.08M +13,309 New
LPC
24
Lion Point Capital
New York
$2.78M +$2.78M +12,000 New
UOTTAIMCU
25
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$2.59M -$398K -1,719 -13%
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