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Spyre Therapeutics

87 hedge funds and large institutions have $352M invested in Spyre Therapeutics in 2020 Q2 according to their latest regulatory filings, with 25 funds opening new positions, 43 increasing their positions, 13 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

267% more capital invested

Capital invested by funds: $95.8M → $352M (+$256M)

231% more repeat investments, than reductions

Existing positions increased: 43 | Existing positions reduced: 13

213% more first-time investments, than exits

New positions opened: 25 | Existing positions closed: 8

50% more funds holding in top 10

Funds holding in top 10: 23 (+1)

24% more funds holding

Funds holding: 7087 (+17)

0.58% more ownership

Funds ownership: 2.83%3.41% (+0.58%)

Holders
87
Holders Change
+17
Holders Change %
+24.29%
% of All Funds
1.78%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.06%
New
25
Increased
43
Reduced
13
Closed
8
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
BBA
1
Baker Bros. Advisors
New York
$40.5M +$20.3M +106,640 +156%
O
2
OrbiMed
New York
$37.1M +$8.76M +46,000 +40%
BlackRock
3
BlackRock
New York
$29.8M +$9.96M +52,314 +69%
NCM
4
Nantahala Capital Management
Connecticut
$29.6M +$2.69M +14,103 +12%
Adage Capital Partners
5
Adage Capital Partners
Massachusetts
$26.8M +$10.8M +56,936 +97%
BCLSI
6
Bain Capital Life Sciences Investors
Massachusetts
$25M +$20.6M +108,000 New
Vanguard Group
7
Vanguard Group
Pennsylvania
$17.1M +$5.04M +26,448 +56%
ACM
8
Aisling Capital Management
New York
$15.6M +$3.05M +16,000 +31%
RSCM
9
Rock Springs Capital Management
Maryland
$14.7M +$6.02M +31,621 +99%
Marshall Wace
10
Marshall Wace
United Kingdom
$11.6M +$3.12M +16,391 +49%
AG
11
Artal Group
Luxembourg
$10.2M +$5.33M +28,000 +175%
SB
12
Samsara BioCapital
California
$8.95M +$7.37M +38,700 New
DM
13
Deerfield Management
New York
$7.63M +$6.28M +33,000 New
State Street
14
State Street
Massachusetts
$6.04M +$1.38M +7,244 +38%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$5.39M +$2.01M +10,543 +83%
Renaissance Technologies
16
Renaissance Technologies
New York
$5.13M -$347K -1,824 -8%
BC
17
Boxer Capital
California
$5.09M +$4.19M +22,000 New
Northern Trust
18
Northern Trust
Illinois
$4.62M +$1.54M +8,106 +68%
Dimensional Fund Advisors
19
Dimensional Fund Advisors
Texas
$4.61M -$222K -1,164 -6%
Goldman Sachs
20
Goldman Sachs
New York
$4.21M +$253K +1,326 +8%
DCM
21
Driehaus Capital Management
Illinois
$3.98M +$3.27M +17,188 New
SCM
22
Soleus Capital Management
Connecticut
$3.42M -$1.27M -6,666 -31%
Assenagon Asset Management
23
Assenagon Asset Management
Luxembourg
$3.08M +$2.53M +13,309 New
LPC
24
Lion Point Capital
New York
$2.77M +$2.29M +12,000 New
UOTTAIMCU
25
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$2.59M -$327K -1,719 -13%

SYRE Hedge Fund Activity: Q2 2020 in Review

87 of the 4,878 institutional investors tracked by Wall St. Rank reported a position in Spyre Therapeutics (SYRE) for Q2 2020, worth a combined $352M — up 267% from $95.8M a quarter earlier.

Buyers outnumbered sellers: 25 funds opened new SYRE positions and 8 closed out — a net gain of 17 holders — while 43 added to existing stakes and 13 trimmed.

The largest buyer was Bain Capital Life Sciences Investors, opening a new position worth an estimated $20.6M. The largest seller was Soleus Capital Management, cutting an estimated $1.27M.

  • 87 institutional investors held Spyre Therapeutics (SYRE) as of Q2 2020, up from 70 in Q1 2020.
  • Funds reported $352M of Spyre Therapeutics stock for Q2 2020, up 267% quarter-over-quarter.
  • 25 funds opened new Spyre Therapeutics positions in Q2 2020 and 8 closed out, a net change of +17 holders.
  • The largest Spyre Therapeutics buyer in Q2 2020 was Bain Capital Life Sciences Investors, an estimated $20.6M added.
  • The largest Spyre Therapeutics seller in Q2 2020 was Soleus Capital Management, an estimated $1.27M sold.

Based on aggregated 13F filings for Q2 2020.