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Spyre Therapeutics
SYRE

Overview Fund Activity

38 hedge funds and large institutions have $84.1M invested in Spyre Therapeutics in 2018 Q1 according to their latest regulatory filings, with 11 funds opening new positions, 16 increasing their positions, 0 reducing their positions, and 4 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
38
Holders Change
+7
Holders Change %
+22.58%
% of All Funds
0.87%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
11
Increased
16
Reduced
–
Closed
4
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$2.48M
2
Jennison Associates
Jennison Associates
New York
+$1.11M
3
Renaissance Technologies
Renaissance Technologies
New York
+$694K
4
Vanguard Group
Vanguard Group
Pennsylvania
+$656K
5
DZ Bank
DZ Bank
Germany
+$649K

Top Sellers

1
DCM
DAFNA Capital Management
California
-$1.89M
2
Jacobs Levy Equity Management
Jacobs Levy Equity Management
New Jersey
-$85K
3
Bank of New York Mellon
Bank of New York Mellon
New York
-$72K
4
Macquarie Group
Macquarie Group
Australia
-$9K
Name Holding Trade Value Shares
Change 		Shares
Change %
NCM
1
Nantahala Capital Management
Connecticut
$18.3M – – –
Jennison Associates
2
Jennison Associates
New York
$14.9M +$1.11M +4,466 +8%
O
3
OrbiMed
New York
$14.6M – – –
BBA
4
Baker Bros. Advisors
New York
$11.3M – – –
UOTTAIMCU
5
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$5.21M – – –
RSCM
6
Rock Springs Capital Management
Maryland
$5.2M – – –
Vanguard Group
7
Vanguard Group
Pennsylvania
$3.35M +$656K +2,647 +24%
Adage Capital Partners
8
Adage Capital Partners
Massachusetts
$2.48M +$2.48M +10,000 New
Renaissance Technologies
9
Renaissance Technologies
New York
$1.01M +$694K +2,796 +218%
BCM
10
Bridgeway Capital Management
Texas
$992K – – –
Dimensional Fund Advisors
11
Dimensional Fund Advisors
Texas
$911K +$552K +2,227 +154%
Millennium Management
12
Millennium Management
New York
$736K +$599K +2,415 +437%
DZ Bank
13
DZ Bank
Germany
$649K +$649K +2,618 New
EI
14
EAM Investors
California
$563K +$563K +2,269 New
JPMorgan Chase & Co
15
JPMorgan Chase & Co
New York
$502K +$442K +1,784 +737%
Acadian Asset Management
16
Acadian Asset Management
Massachusetts
$307K +$207K +831 +206%
Geode Capital Management
17
Geode Capital Management
Massachusetts
$304K – – –
Wells Fargo
18
Wells Fargo
California
$271K +$43.2K +174 +19%
William Blair & Company
19
William Blair & Company
Illinois
$270K +$159K +640 +143%
UBS Group
20
UBS Group
Switzerland
$244K +$231K +930 +1,755%
BlackRock
21
BlackRock
New York
$243K +$25.3K +102 +12%
LF
22
Lee Financial
Texas
$222K – – –
SIM
23
Spark Investment Management
New York
$188K +$77.2K +312 +70%
ARTA
24
A.R.T. Advisors
New York
$183K +$183K +739 New
Northern Trust
25
Northern Trust
Illinois
$181K +$17.6K +71 +11%
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