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Spyre Therapeutics

59 hedge funds and large institutions have $140M invested in Spyre Therapeutics in 2018 Q3 according to their latest regulatory filings, with 8 funds opening new positions, 23 increasing their positions, 17 reducing their positions, and 13 closing their positions.

New
Increased
Maintained
Reduced
Closed

35% more repeat investments, than reductions

Existing positions increased: 23 | Existing positions reduced: 17

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

0.03% less ownership

Funds ownership: 2.69%2.65% (-0.03%)

8% less funds holding

Funds holding: 6459 (-5)

10% less capital invested

Capital invested by funds: $155M → $140M (-$15.2M)

38% less first-time investments, than exits

New positions opened: 8 | Existing positions closed: 13

Holders
59
Holders Change
-5
Holders Change %
-7.81%
% of All Funds
1.35%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.02%
New
8
Increased
23
Reduced
17
Closed
13
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
NCM
1
Nantahala Capital Management
Connecticut
$24.2M +$2.94M +12,568 +14%
O
2
OrbiMed
New York
$20.7M +$2.8M +12,000 +16%
Jennison Associates
3
Jennison Associates
New York
$14.7M +$64.9K +278 +0.5%
BBA
4
Baker Bros. Advisors
New York
$13.3M
BlackRock
5
BlackRock
New York
$9.85M +$1.93M +8,260 +25%
Adage Capital Partners
6
Adage Capital Partners
Massachusetts
$8.76M +$234K +1,000 +3%
Vanguard Group
7
Vanguard Group
Pennsylvania
$7.21M +$515K +2,207 +8%
SFM
8
Sphera Funds Management
Israel
$6.25M +$1.35M +5,759 +28%
RSCM
9
Rock Springs Capital Management
Maryland
$6.22M
Renaissance Technologies
10
Renaissance Technologies
New York
$4.47M -$569K -2,438 -12%
UOTTAIMCU
11
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$3.21M -$50.5K -216 -2%
Man Group
12
Man Group
United Kingdom
$2.87M -$245K -1,047 -8%
Point72 Asset Management
13
Point72 Asset Management
Connecticut
$2.54M +$2.48M +10,625 New
State Street
14
State Street
Massachusetts
$2.38M +$233K +999 +11%
Northern Trust
15
Northern Trust
Illinois
$1.74M +$43.4K +186 +3%
Dimensional Fund Advisors
16
Dimensional Fund Advisors
Texas
$1.59M +$696K +2,979 +81%
Geode Capital Management
17
Geode Capital Management
Massachusetts
$1.48M +$64.2K +275 +5%
BCM
18
Bridgeway Capital Management
Texas
$981K +$23.4K +100 +3%
DAM
19
Deltec Asset Management
New York
$862K -$576K -2,467 -41%
Squarepoint
20
Squarepoint
New York
$684K +$359K +1,536 +116%
Acadian Asset Management
21
Acadian Asset Management
Massachusetts
$519K -$176K -755 -26%
UBS Group
22
UBS Group
Switzerland
$509K -$195K -834 -28%
JP Morgan Chase
23
JP Morgan Chase
New York
$437K -$694K -2,973 -62%
Bank of New York Mellon
24
Bank of New York Mellon
New York
$424K +$27.3K +117 +7%
Deutsche Bank
25
Deutsche Bank
Germany
$356K -$1.39M -5,931 -80%

SYRE Hedge Fund Activity: Q3 2018 in Review

59 of the 4,375 institutional investors tracked by Wall St. Rank reported a position in Spyre Therapeutics (SYRE) for Q3 2018, worth a combined $140M — down 9.8% from $155M a quarter earlier.

Sellers outnumbered buyers: 13 funds closed out of SYRE and 8 opened new positions — a net loss of 5 holders — while 17 trimmed existing stakes and 23 added.

The largest buyer was Nantahala Capital Management, adding an estimated $2.94M. The largest seller was Millennium Management, exiting entirely with an estimated $5.04M sold.

  • 59 institutional investors held Spyre Therapeutics (SYRE) as of Q3 2018, down from 64 in Q2 2018.
  • Funds reported $140M of Spyre Therapeutics stock for Q3 2018, down 9.8% quarter-over-quarter.
  • 8 funds opened new Spyre Therapeutics positions in Q3 2018 and 13 closed out, a net change of -5 holders.
  • The largest Spyre Therapeutics buyer in Q3 2018 was Nantahala Capital Management, an estimated $2.94M added.
  • The largest Spyre Therapeutics seller in Q3 2018 was Millennium Management, an estimated $5.04M sold.

Based on aggregated 13F filings for Q3 2018.