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Spyre Therapeutics
SYRE

Overview Fund Activity

59 hedge funds and large institutions have $140M invested in Spyre Therapeutics in 2018 Q3 according to their latest regulatory filings, with 8 funds opening new positions, 23 increasing their positions, 17 reducing their positions, and 13 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
59
Holders Change
-5
Holders Change %
-7.81%
% of All Funds
1.35%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
8
Increased
23
Reduced
17
Closed
13
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
NCM
Nantahala Capital Management
Connecticut
+$3.01M
2
O
OrbiMed
New York
+$2.87M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
+$2.54M
4
BlackRock
BlackRock
New York
+$1.98M
5
SFM
Sphera Funds Management
Israel
+$1.38M

Top Sellers

1
Millennium Management
Millennium Management
New York
-$5.04M
2
SFM
Soros Fund Management
New York
-$2.18M
3
SI
SCP Investment
California
-$1.65M
4
Deutsche Bank
Deutsche Bank
Germany
-$1.42M
5
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
-$711K
Name Holding Trade Value Shares
Change 		Shares
Change %
NCM
1
Nantahala Capital Management
Connecticut
$24.2M +$3.01M +12,568 +14%
O
2
OrbiMed
New York
$20.7M +$2.87M +12,000 +16%
Jennison Associates
3
Jennison Associates
New York
$14.7M +$66.5K +278 +0.5%
BBA
4
Baker Bros. Advisors
New York
$13.3M – – –
BlackRock
5
BlackRock
New York
$9.85M +$1.98M +8,260 +25%
Adage Capital Partners
6
Adage Capital Partners
Massachusetts
$8.76M +$239K +1,000 +3%
Vanguard Group
7
Vanguard Group
Pennsylvania
$7.21M +$528K +2,207 +8%
SFM
8
Sphera Funds Management
Israel
$6.25M +$1.38M +5,759 +28%
RSCM
9
Rock Springs Capital Management
Maryland
$6.22M – – –
Renaissance Technologies
10
Renaissance Technologies
New York
$4.47M -$583K -2,438 -12%
UOTTAIMCU
11
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$3.21M -$51.7K -216 -2%
Man Group
12
Man Group
United Kingdom
$2.87M -$251K -1,047 -8%
Point72 Asset Management
13
Point72 Asset Management
Connecticut
$2.54M +$2.54M +10,625 New
State Street
14
State Street
Massachusetts
$2.38M +$239K +999 +11%
Northern Trust
15
Northern Trust
Illinois
$1.74M +$44.5K +186 +3%
Dimensional Fund Advisors
16
Dimensional Fund Advisors
Texas
$1.59M +$713K +2,979 +81%
Geode Capital Management
17
Geode Capital Management
Massachusetts
$1.48M +$65.8K +275 +5%
BCM
18
Bridgeway Capital Management
Texas
$981K +$23.9K +100 +3%
DAM
19
Deltec Asset Management
New York
$862K -$590K -2,467 -41%
Squarepoint
20
Squarepoint
New York
$684K +$367K +1,536 +116%
Acadian Asset Management
21
Acadian Asset Management
Massachusetts
$519K -$181K -755 -26%
UBS Group
22
UBS Group
Switzerland
$509K -$200K -834 -28%
JPMorgan Chase & Co
23
JPMorgan Chase & Co
New York
$437K -$711K -2,973 -62%
Bank of New York Mellon
24
Bank of New York Mellon
New York
$424K +$28K +117 +7%
Deutsche Bank
25
Deutsche Bank
Germany
$356K -$1.42M -5,931 -80%
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