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Spyre Therapeutics

131 hedge funds and large institutions have $1.39B invested in Spyre Therapeutics in 2024 Q4 according to their latest regulatory filings, with 34 funds opening new positions, 63 increasing their positions, 20 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
131
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$161K
Puts
$79K
Net Calls
Net Calls Change

Top Buyers

1 +$62.1M
2 +$34.5M
3 +$22.3M
4
BlackRock
BlackRock
New York
+$21.6M
5
Goldman Sachs
Goldman Sachs
New York
+$17M

Top Sellers

1 -$32.8M
2 -$22.9M
3 -$17.6M
4
PA
Perceptive Advisors
New York
-$8.73M
5
Bank of America
Bank of America
North Carolina
-$7.35M
Name Holding Trade Value Shares
Change
Change in
Stake
1
$205M
2
$93.5M
3
$84.3M
4
$79.1M
5
$66.3M
6
$65.3M
7
$62.5M
8
$60M
9
$59.9M
10
$46.3M
11
$39.1M
12
$37.4M
13
$35.6M
14
$33.9M
15
$28.3M
16
$25.4M
17
$25.1M
18
$24M
19
$22.5M
20
$19.2M
21
$17.7M
22
$17.5M
23
$17.4M
24
$12.7M
25
$11.8M