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Spyre Therapeutics

43 hedge funds and large institutions have $31.9M invested in Spyre Therapeutics in 2023 Q2 according to their latest regulatory filings, with 15 funds opening new positions, 4 increasing their positions, 8 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

166% more capital invested

Capital invested by funds: $12M → $31.9M (+$19.9M)

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

1.81% more ownership

Funds ownership: 2.53%4.34% (+1.8%)

6% less first-time investments, than exits

New positions opened: 15 | Existing positions closed: 16

2% less funds holding

Funds holding: 4443 (-1)

50% less repeat investments, than reductions

Existing positions increased: 4 | Existing positions reduced: 8

100% less call options, than puts

Call options by funds: $0 | Put options by funds: $1K

Holders
43
Holders Change
-1
Holders Change %
-2.27%
% of All Funds
0.68%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
15
Increased
4
Reduced
8
Closed
16
Calls
Puts
$1K
Net Calls
-$1K
Net Calls Change
-$1K
Name Holding Trade Value Shares
Change
Change in
Stake
FFM
1
Fairmount Funds Management
Pennsylvania
$4.26M +$1.79M +378,422 New
Wellington Management Group
2
Wellington Management Group
Massachusetts
$3.97M +$1.67M +352,767 New
VA
3
VR Adviser
New York
$2.86M +$1.2M +253,729 New
EC
4
EcoR1 Capital
California
$2.25M +$948K +200,000 New
AAA
5
Affinity Asset Advisors
New York
$2.21M +$929K +196,000 New
DCM
6
Driehaus Capital Management
Illinois
$2.09M +$881K +185,734 New
NCM
7
Nantahala Capital Management
Connecticut
$1.85M -$86.6K -18,272 -10%
SCM
8
Suvretta Capital Management
New York
$1.83M
RSCM
9
Rock Springs Capital Management
Maryland
$1.54M
BBA
10
Baker Bros. Advisors
New York
$1.54M
LGM
11
Logos Global Management
California
$1.42M +$596K +125,715 New
CC
12
Commodore Capital
New York
$1.31M +$552K +116,324 New
Millennium Management
13
Millennium Management
New York
$1.11M -$243K -51,330 -34%
ACM
14
Aisling Capital Management
New York
$762K
Acadian Asset Management
15
Acadian Asset Management
Massachusetts
$625K
SB
16
Samsara BioCapital
California
$398K
Vanguard Group
17
Vanguard Group
Pennsylvania
$292K -$256K -53,982 -68%
Geode Capital Management
18
Geode Capital Management
Massachusetts
$271K
Goldman Sachs
19
Goldman Sachs
New York
$252K +$106K +22,346 New
BlackRock
20
BlackRock
New York
$238K -$22.7K -4,790 -18%
Renaissance Technologies
21
Renaissance Technologies
New York
$177K +$40.2K +8,476 +117%
ACA
22
Avoro Capital Advisors
New York
$129K +$54.3K +11,458 New
UOTTAIMCU
23
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$111K
CG
24
Carlyle Group
District of Columbia
$108K
State Street
25
State Street
Massachusetts
$87.9K -$3.77K -796 -9%

SYRE Hedge Fund Activity: Q2 2023 in Review

43 of the 6,369 institutional investors tracked by Wall St. Rank reported a position in Spyre Therapeutics (SYRE) for Q2 2023, worth a combined $31.9M — up 166% from $12M a quarter earlier.

Sellers outnumbered buyers: 16 funds closed out of SYRE and 15 opened new positions — a net loss of 1 holder — while 8 trimmed existing stakes and 4 added.

The largest buyer was Fairmount Funds Management, opening a new position worth an estimated $1.79M. The largest seller was Bain Capital Life Sciences Investors, exiting entirely with an estimated $1.55M sold.

  • 43 institutional investors held Spyre Therapeutics (SYRE) as of Q2 2023, down from 44 in Q1 2023.
  • Funds reported $31.9M of Spyre Therapeutics stock for Q2 2023, up 166% quarter-over-quarter.
  • 15 funds opened new Spyre Therapeutics positions in Q2 2023 and 16 closed out, a net change of -1 holder.
  • The largest Spyre Therapeutics buyer in Q2 2023 was Fairmount Funds Management, an estimated $1.79M added.
  • The largest Spyre Therapeutics seller in Q2 2023 was Bain Capital Life Sciences Investors, an estimated $1.55M sold.

Based on aggregated 13F filings for Q2 2023.