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Spyre Therapeutics

85 hedge funds and large institutions have $189M invested in Spyre Therapeutics in 2021 Q4 according to their latest regulatory filings, with 18 funds opening new positions, 26 increasing their positions, 22 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
85
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$263K
Puts
$248K
Net Calls
Net Calls Change

Top Buyers

1 +$6.16M
2 +$4.01M
3 +$1.96M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$946K
5
CAM
ClariVest Asset Management
California
+$832K

Top Sellers

1 -$11.9M
2 -$5.03M
3 -$1.64M
4
ACM
Altium Capital Management
New York
-$1.5M
5
Marshall Wace
Marshall Wace
United Kingdom
-$1.3M
Name Holding Trade Value Shares
Change
Change in
Stake
1
$16.2M
2
$14.2M
3
$14M
4
$13.5M
5
$13.4M
6
$12.2M
7
$11.7M
8
$10.1M
9
$8.03M
10
$7.49M
11
$6.89M
12
$5.39M
13
$4.96M
14
$4.75M
15
$4.32M
16
$4.2M
17
$3.6M
18
$3.28M
19
$3.26M
20
$2.37M
21
$2.11M
22
$1.98M
23
$1.66M
24
$1.43M
25
$1.4M