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Spyre Therapeutics
SYRE

Overview Fund Activity

70 hedge funds and large institutions have $95.8M invested in Spyre Therapeutics in 2020 Q1 according to their latest regulatory filings, with 9 funds opening new positions, 23 increasing their positions, 22 reducing their positions, and 6 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
70
Holders Change
+2
Holders Change %
+2.94%
% of All Funds
1.55%
Holding in Top 10
2
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-50%
% of All Funds
0.04%
New
9
Increased
23
Reduced
22
Closed
6
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
AG
Artal Group
Luxembourg
+$466K
2
SCM
Soleus Capital Management
Connecticut
+$365K
3
Jacobs Levy Equity Management
Jacobs Levy Equity Management
New Jersey
+$186K
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$127K
5
Renaissance Technologies
Renaissance Technologies
New York
+$111K

Top Sellers

1
Russell Investments Group
Russell Investments Group
United Kingdom
-$417K
2
Man Group
Man Group
United Kingdom
-$315K
3
State of Wisconsin Investment Board
State of Wisconsin Investment Board
Wisconsin
-$303K
4
PAWC
P.A.W. Capital
Connecticut
-$285K
5
Morgan Stanley
Morgan Stanley
New York
-$152K
Name Holding Trade Value Shares
Change 		Shares
Change %
O
1
OrbiMed
New York
$13.4M – – –
NCM
2
Nantahala Capital Management
Connecticut
$13.1M – – –
BlackRock
3
BlackRock
New York
$8.9M -$61.8K -530 -0.7%
BBA
4
Baker Bros. Advisors
New York
$7.99M – – –
Adage Capital Partners
5
Adage Capital Partners
Massachusetts
$6.84M – – –
ACM
6
Aisling Capital Management
New York
$6.02M – – –
Vanguard Group
7
Vanguard Group
Pennsylvania
$5.52M +$19.2K +165 +0.3%
Marshall Wace
8
Marshall Wace
United Kingdom
$3.91M +$26.8K +230 +0.7%
RSCM
9
Rock Springs Capital Management
Maryland
$3.73M – – –
Renaissance Technologies
10
Renaissance Technologies
New York
$2.79M +$111K +950 +4%
SCM
11
Soleus Capital Management
Connecticut
$2.5M +$365K +3,133 +17%
Dimensional Fund Advisors
12
Dimensional Fund Advisors
Texas
$2.46M -$13.2K -113 -0.5%
State Street
13
State Street
Massachusetts
$2.2M +$32.2K +276 +1%
Goldman Sachs
14
Goldman Sachs
New York
$1.97M -$95.4K -819 -5%
AG
15
Artal Group
Luxembourg
$1.86M +$466K +4,000 +33%
UOTTAIMCU
16
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$1.5M – – –
Geode Capital Management
17
Geode Capital Management
Massachusetts
$1.49M +$27.5K +236 +2%
Northern Trust
18
Northern Trust
Illinois
$1.38M +$11.9K +102 +0.9%
A
19
Abingworth
United Kingdom
$1.1M – – –
RWM
20
Ritholtz Wealth Management
New York
$1.05M -$93.2K -800 -8%
BCM
21
Bridgeway Capital Management
Texas
$534K +$56K +480 +12%
Bank of New York Mellon
22
Bank of New York Mellon
New York
$443K +$22.1K +190 +5%
Nuveen Asset Management
23
Nuveen Asset Management
Illinois
$413K -$1.63K -14 -0.4%
Wells Fargo
24
Wells Fargo
California
$319K +$59.5K +511 +23%
Russell Investments Group
25
Russell Investments Group
United Kingdom
$290K -$417K -3,594 -59%
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