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Spyre Therapeutics

94 hedge funds and large institutions have $275M invested in Spyre Therapeutics in 2020 Q3 according to their latest regulatory filings, with 17 funds opening new positions, 23 increasing their positions, 31 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
94
Holders Change
+7
Holders Change %
+8.05%
% of All Funds
1.9%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.04%
New
17
Increased
23
Reduced
31
Closed
10
Calls
$1K
Puts
Net Calls
+$1K
Net Calls Change
+$1K
Name Holding Trade Value Shares
Change
Shares
Change %
BBA
1
Baker Bros. Advisors
New York
$31.1M
O
2
OrbiMed
New York
$28.5M
BlackRock
3
BlackRock
New York
$22.2M -$631K -3,562 -3%
NCM
4
Nantahala Capital Management
Connecticut
$22.1M -$577K -3,256 -3%
Adage Capital Partners
5
Adage Capital Partners
Massachusetts
$21.2M +$709K +4,000 +3%
BCLSI
6
Bain Capital Life Sciences Investors
Massachusetts
$19.1M
Vanguard Group
7
Vanguard Group
Pennsylvania
$13.1M +$28K +158 +0.2%
ACM
8
Aisling Capital Management
New York
$12M
RSCM
9
Rock Springs Capital Management
Maryland
$11.3M
Marshall Wace
10
Marshall Wace
United Kingdom
$8.81M -$46.1K -260 -0.5%
PAMU
11
Pictet Asset Management (UK)
United Kingdom
$8.05M +$8.05M +45,438 New
AG
12
Artal Group
Luxembourg
$7.41M -$390K -2,200 -5%
SB
13
Samsara BioCapital
California
$6.27M -$594K -3,351 -9%
State Street
14
State Street
Massachusetts
$4.66M +$28.7K +162 +0.6%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$4.03M -$101K -568 -2%
BC
16
Boxer Capital
California
$3.9M
SCM
17
Suvretta Capital Management
New York
$3.75M +$2.91M +16,447 +349%
Dimensional Fund Advisors
18
Dimensional Fund Advisors
Texas
$3.54M +$5.14K +29 +0.1%
Northern Trust
19
Northern Trust
Illinois
$3.35M -$193K -1,091 -5%
Goldman Sachs
20
Goldman Sachs
New York
$3.17M -$49.6K -280 -2%
DCM
21
Driehaus Capital Management
Illinois
$2.99M -$53.3K -301 -2%
OM
22
Opaleye Management
Massachusetts
$2.66M +$2.66M +15,000 New
Renaissance Technologies
23
Renaissance Technologies
New York
$2.46M -$1.47M -8,272 -37%
Axa
24
Axa
France
$2.16M +$2.16M +12,205 New
LPC
25
Lion Point Capital
New York
$2.13M