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Spyre Therapeutics

Name Holding Trade Value Shares
Change
Change in
Stake
O
1
OrbiMed
New York
$10.9M +$617K +4,372 +8%
Jennison Associates
2
Jennison Associates
New York
$10.8M +$49.7K +352 +0.6%
UOTTAIMCU
3
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$3.91M
RSCM
4
Rock Springs Capital Management
Maryland
$3.9M
DCM
5
DAFNA Capital Management
California
$2.61M
BBA
6
Baker Bros. Advisors
New York
$1.42M -$1.21M -8,570 -53%
SCM
7
Sio Capital Management
New York
$1.27M -$105K -743 -10%
Vanguard Group
8
Vanguard Group
Pennsylvania
$1.03M +$468K +3,314 +151%
Alyeska Investment Group
9
Alyeska Investment Group
Illinois
$881K -$7.76K -55 -1%
NI
10
Numeric Investors
Massachusetts
$294K +$223K +1,580 New
Renaissance Technologies
11
Renaissance Technologies
New York
$270K +$204K +1,448 New
Geode Capital Management
12
Geode Capital Management
Massachusetts
$246K +$55.6K +394 +42%
LF
13
Lee Financial
Texas
$167K
Bank of New York Mellon
14
Bank of New York Mellon
New York
$157K +$119K +842 New
Northern Trust
15
Northern Trust
Illinois
$123K +$93.2K +660 New
Wells Fargo
16
Wells Fargo
California
$117K -$8.89K -63 -9%
BlackRock
17
BlackRock
New York
$113K +$85.6K +606 New
Squarepoint
18
Squarepoint
New York
$91K +$68.9K +488 New
PA
19
Perceptive Advisors
New York
$43K -$552K -3,910 -94%
Deutsche Bank
20
Deutsche Bank
Germany
$36K +$28K +198 New
IA
21
IFP Advisors
Florida
$21K
Morgan Stanley
22
Morgan Stanley
New York
$20K
UBS Group
23
UBS Group
Switzerland
$7K +$988 +7 +22%
VMI
24
VHCP Management II
New York
-$1.52M -14,005 Closed
Norges Bank
25
Norges Bank
Norway
-$275K -2,528 Closed