Rock Springs Capital Management’s Spyre Therapeutics SYRE Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Shares Change %	Capital Flow	Portfolio Weight	Portfolio Position
2023 Q4	–	Sell	-136,556	Closed	-$1.67M	–	113
2023 Q3	$1.67M	Hold	136,556	–	–	0.04%	101
2023 Q2	$1.54M	Hold	136,556	–	–	0.04%	109
2023 Q1	$990K	Hold	136,556	–	–	0.02%	111
2022 Q4	$1.54M	Hold	136,556	–	–	0.04%	108
2022 Q3	$1.8M	Buy	136,556 +13,675	+11%	+$180K	0.05%	114
2022 Q2	$1.55M	Buy	122,881 +50,424	+70%	+$637K	0.05%	119
2022 Q1	$4.17M	Buy	72,457 +9,365	+15%	+$538K	0.1%	108
2021 Q4	$7.49M	Hold	63,092	–	–	0.17%	103
2021 Q3	$12.5M	Hold	63,092	–	–	0.26%	97
2021 Q2	$11M	Hold	63,092	–	–	0.22%	107
2021 Q1	$12.5M	Sell	63,092 -108	-0.2%	-$21.4K	0.27%	98
2020 Q4	$12.4M	Sell	63,200 -421	-0.7%	-$82.8K	0.26%	102
2020 Q3	$11.3M	Hold	63,621	–	–	0.29%	96
2020 Q2	$14.7M	Buy	63,621 +31,621	+99%	+$7.31M	0.4%	86
2020 Q1	$3.73M	Hold	32,000	–	–	0.15%	110
2019 Q4	$6.11M	Hold	32,000	–	–	0.19%	102
2019 Q3	$6.15M	Hold	32,000	–	–	0.25%	94
2019 Q2	$5.48M	Hold	32,000	–	–	0.2%	97
2019 Q1	$6.44M	Buy	32,000 +6,000	+23%	+$1.21M	0.25%	98
2018 Q4	$4.87M	Hold	26,000	–	–	0.23%	96
2018 Q3	$6.22M	Hold	26,000	–	–	0.23%	105
2018 Q2	$6.88M	Buy	26,000 +5,036	+24%	+$1.33M	0.26%	104
2018 Q1	$5.2M	Hold	20,964	–	–	0.22%	117
2017 Q4	$2.84M	Hold	20,964	–	–	0.13%	126
2017 Q3	$2.58M	Hold	20,964	–	–	0.12%	122
2017 Q2	$2.01M	Hold	20,964	–	–	0.1%	129
2017 Q1	$3.9M	Hold	20,964	–	–	0.23%	98
2016 Q4	$2.28M	Hold	20,964	–	–	0.15%	110
2016 Q3	$3.36M	Hold	20,964	–	–	0.21%	105
2016 Q2	$2.55M	Buy	+20,964	New	+$2.55M	0.19%	107