Group One Trading
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Group One Trading’s Spyre Therapeutics SYRE Stock Holding History

Group One Trading’s Portfolio SYRE Stock Details SYRE Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		– Sell
-901
Closed -$65.7K – 8487
2026
Q1 		$45.4K Buy
901
+501
+125% +$18.9K ﹤0.01% 5329
2025
Q4 		$13.1K Buy
+400
New +$10.5K ﹤0.01% 6645
2023
Q3 		– Sell
-23
Closed -$304 – 8284
2023
Q2 		$258 Sell
23
-92
-80% -$436 ﹤0.01% 7444
2023
Q1 		$836 Sell
115
-12
-9% -$132 ﹤0.01% 6823
2022
Q4 		$1.43K Buy
127
+3
+2% +$54 ﹤0.01% 6749
2022
Q3 		$2K Hold
124
– – ﹤0.01% 7207
2022
Q2 		$2K Buy
124
+4
+3% +$140 ﹤0.01% 7444
2022
Q1 		$7K Sell
120
-92
-43% -$7.73K ﹤0.01% 7317
2021
Q4 		$25K Buy
+212
New +$33.5K ﹤0.01% 6841
2021
Q3 		– Sell
-12
Closed -$2K – 8771
2021
Q2 		$2K Buy
12
+4
+50% +$727 ﹤0.01% 7966
2021
Q1 		$2K Hold
8
– – ﹤0.01% 7404
2020
Q4 		$2K Buy
8
+4
+100% +$829 ﹤0.01% 6274
2020
Q3 		$1K Buy
+4
New +$740 ﹤0.01% 5959

Other funds holding SYRE

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
PA
Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return
RI
RTW Investments New York $11.7B AUM 174.13% 1-Year Est. Return
PBA
Paradigm Biocapital Advisors New York $5.34B AUM 380.18% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
VA
VR Adviser New York $3.3B AUM 525.74% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $999B AUM 46.22% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return

Group One Trading's SYRE Position: Q2 2026 in Review

Group One Trading sold out of Spyre Therapeutics (SYRE) in Q2 2026, closing a stake of 901 shares — an estimated $65.7K sold.

Group One Trading first reported a position in SYRE in Q3 2020 and held it in 13 quarters. The position peaked at $45.4K in Q1 2026. 265 funds tracked by Wall St. Rank hold SYRE as of Q2 2026.

  • Group One Trading reported no remaining Spyre Therapeutics position as of Q2 2026 after selling out during the quarter.
  • Group One Trading sold 901 Spyre Therapeutics shares in Q2 2026, an estimated $65.7K.
  • Group One Trading first reported a position in Spyre Therapeutics in Q3 2020 and held it in 13 quarters.
  • Group One Trading's Spyre Therapeutics position peaked at $45.4K in Q1 2026.
  • 265 funds tracked by Wall St. Rank held Spyre Therapeutics as of Q2 2026.

Based on Group One Trading's 13F filing for Q2 2026, filed 14 Aug 2026.