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Karyopharm Therapeutics
KPTI

Overview Fund Activity

153 hedge funds and large institutions have $608M invested in Karyopharm Therapeutics in 2021 Q2 according to their latest regulatory filings, with 21 funds opening new positions, 54 increasing their positions, 56 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
153
Holders Change
-18
Holders Change %
-10.53%
% of All Funds
2.67%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
21
Increased
54
Reduced
56
Closed
38
Calls
$4.62M
Puts
$14.1M
Net Calls
-$9.52M
Net Calls Change
-$8.17M

Top Buyers

1
RCMNY
Rubric Capital Management (New York)
New York
+$43.9M
2
BlackRock
BlackRock
New York
+$10.6M
3
LOAMS
Lombard Odier Asset Management (Switzerland)
Switzerland
+$5.64M
4
State Street
State Street
Massachusetts
+$5M
5
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
+$3.96M

Top Sellers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$14.2M
2
Wellington Management Group
Wellington Management Group
Massachusetts
-$13.6M
3
LCM
Laurion Capital Management
New York
-$9.49M
4
CLOS
Compagnie Lombard Odier SCmA
Switzerland
-$8.73M
5
Two Sigma Investments
Two Sigma Investments
New York
-$6.67M
Name Holding Trade Value Shares
Change 		Shares
Change %
AIG
151
American International Group
New York
$416 -$10 -65 -2%
Nisa Investment Advisors
152
Nisa Investment Advisors
Missouri
$8 -$33 -217 -80%
Adage Capital Partners
153
Adage Capital Partners
Massachusetts
– -$14.2M -89,987 Closed
CLOS
154
Compagnie Lombard Odier SCmA
Switzerland
– -$8.73M -55,312 Closed
SSA
155
Schonfeld Strategic Advisors
New York
– -$1.88M -11,914 Closed
JAMH
156
Junson Asset Management (HK)
Hong Kong
– -$1.57M -10,000 Closed
Qube Research & Technologies (QRT)
157
Qube Research & Technologies (QRT)
United Kingdom
– -$1.54M -9,763 Closed
California Public Employees Retirement System
158
California Public Employees Retirement System
California
– -$1.5M -9,533 Closed
PFC
159
Phocas Financial Corp
California
– -$1.43M -9,054 Closed
Fidelity Investments
160
Fidelity Investments
Massachusetts
– -$833K -5,281 Closed
KOCAA
161
Knights of Columbus Asset Advisors
Connecticut
– -$761K -4,823 Closed
PP
162
PDT Partners
New York
– -$747K -4,735 Closed
DTL
163
Dynamic Technology Lab
Singapore
– -$642K -4,067 Closed
First Trust Advisors
164
First Trust Advisors
Illinois
– -$611K -3,870 Closed
SEC
165
Seven Eight Capital
New York
– -$721K -3,107 Closed
EA
166
Emerald Advisers
Pennsylvania
– -$489K -3,098 Closed
TRSOTSOK
167
Teachers Retirement System of the State of Kentucky
Kentucky
– -$489K -3,098 Closed
DADC
168
D.A. Davidson & Co
Montana
– -$431K -2,733 Closed
BC
169
Bridgefront Capital
Texas
– -$393K -2,492 Closed
IA
170
Insight Advisors
Pennsylvania
– -$306K -2,184 Closed
BCM
171
Bayesian Capital Management
New York
– -$284K -1,800 Closed
ACM
172
AlphaCrest Capital Management
New York
– -$274K -1,733 Closed
MFIM
173
Mesirow Financial Investment Management
Illinois
– -$228K -1,447 Closed
SG Americas Securities
174
SG Americas Securities
New York
– -$171K -1,085 Closed
TC
175
TwinBeech Capital
New York
– -$168K -1,066 Closed
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