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Karyopharm Therapeutics

118 hedge funds and large institutions have $103M invested in Karyopharm Therapeutics in 2023 Q3 according to their latest regulatory filings, with 16 funds opening new positions, 40 increasing their positions, 29 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

331% more call options, than puts

Call options by funds: $785K | Put options by funds: $182K

38% more repeat investments, than reductions

Existing positions increased: 40 | Existing positions reduced: 29

0.27% less ownership

Funds ownership: 4.77%4.5% (-0.27%)

14% less funds holding

Funds holding: 137118 (-19)

29% less capital invested

Capital invested by funds: $145M → $103M (-$42.2M)

54% less first-time investments, than exits

New positions opened: 16 | Existing positions closed: 35

Holders
118
Holders Change
-19
Holders Change %
-13.87%
% of All Funds
1.87%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
16
Increased
40
Reduced
29
Closed
35
Calls
$785K
Puts
$182K
Net Calls
+$603K
Net Calls Change
+$232K
Name Holding Trade Value Shares
Change
Change in
Stake
Alyeska Investment Group
126
Alyeska Investment Group
Illinois
-$862K -32,113 Closed
Two Sigma Investments
127
Two Sigma Investments
New York
-$622K -23,170 Closed
E
128
Ergoteles
New York
-$425K -15,827 Closed
HF
129
HRT Financial
New York
-$403K -15,035 Closed
Swiss National Bank
130
Swiss National Bank
Switzerland
-$400K -14,890 Closed
CSS
131
Cubist Systematic Strategies
Connecticut
-$286K -10,667 Closed
PI
132
Putnam Investments
Massachusetts
-$265K -9,854 Closed
CS
133
Credit Suisse
Switzerland
-$194K -7,236 Closed
Acadian Asset Management
134
Acadian Asset Management
Massachusetts
-$177K -6,596 Closed
VRS
135
Virginia Retirement Systems
Virginia
-$165K -6,133 Closed
UBS AM
136
UBS AM
Illinois
-$356K -6,109 Closed
LCM
137
Laurion Capital Management
New York
-$102K -3,810 Closed
Janus Henderson Group
138
Janus Henderson Group
United Kingdom
-$68.3K -2,537 Closed
DFCM
139
Dark Forest Capital Management
Puerto Rico
-$62.5K -2,330 Closed
YIH
140
Y-Intercept (HK)
Hong Kong
-$60.7K -2,262 Closed
State Board of Administration of Florida Retirement System
141
State Board of Administration of Florida Retirement System
Florida
-$57.6K -2,144 Closed
ASRS
142
Arizona State Retirement System
Arizona
-$51.6K -1,920 Closed
Teacher Retirement System of Texas
143
Teacher Retirement System of Texas
Texas
-$50K -1,856 Closed
Canada Life
144
Canada Life
Manitoba, Canada
-$42K -1,538 Closed
Mariner
145
Mariner
Kansas
-$35.8K -1,332 Closed
DTL
146
Dynamic Technology Lab
Singapore
-$34K -1,253 Closed
SCA
147
Snowden Capital Advisors
New York
-$29K -1,080 Closed
BFG
148
Bleakley Financial Group
New Jersey
-$28.6K -1,064 Closed
SS
149
Simplicity Solutions
Minnesota
-$28.6K -1,064 Closed
PCM
150
Prelude Capital Management
New York
-$28.5K -1,062 Closed

KPTI Hedge Fund Activity: Q3 2023 in Review

118 of the 6,302 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q3 2023, worth a combined $103M — down 29% from $145M a quarter earlier.

Sellers outnumbered buyers: 35 funds closed out of KPTI and 16 opened new positions — a net loss of 19 holders — while 29 trimmed existing stakes and 40 added.

The largest buyer was Jacobs Levy Equity Management, adding an estimated $2.51M. The largest seller was Opaleye Management, exiting entirely with an estimated $3.2M sold.

  • 118 institutional investors held Karyopharm Therapeutics (KPTI) as of Q3 2023, down from 137 in Q2 2023.
  • Funds reported $103M of Karyopharm Therapeutics stock for Q3 2023, down 29% quarter-over-quarter.
  • 16 funds opened new Karyopharm Therapeutics positions in Q3 2023 and 35 closed out, a net change of -19 holders.
  • The largest Karyopharm Therapeutics buyer in Q3 2023 was Jacobs Levy Equity Management, an estimated $2.51M added.
  • The largest Karyopharm Therapeutics seller in Q3 2023 was Opaleye Management, an estimated $3.2M sold.

Based on aggregated 13F filings for Q3 2023.