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Karyopharm Therapeutics
KPTI

Overview Fund Activity

139 hedge funds and large institutions have $499M invested in Karyopharm Therapeutics in 2022 Q1 according to their latest regulatory filings, with 26 funds opening new positions, 42 increasing their positions, 46 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
139
Holders Change
-4
Holders Change %
-2.8%
% of All Funds
2.2%
Holding in Top 10
1
Holding in Top 10 Change
+1
Holding in Top 10 Change %
%
% of All Funds
0.02%
New
26
Increased
42
Reduced
46
Closed
28
Calls
$12M
Puts
$4.09M
Net Calls
+$7.88M
Net Calls Change
+$13.6M

Top Buyers

1
State Street
State Street
Massachusetts
+$40.2M
2
CC
Commodore Capital
New York
+$26.2M
3
ITP
Iron Triangle Partners
Connecticut
+$14.7M
4
Morgan Stanley
Morgan Stanley
New York
+$12.9M
5
Bank of America
Bank of America
North Carolina
+$6.35M

Top Sellers

1
Alkeon Capital Management
Alkeon Capital Management
New York
-$12.6M
2
BlackRock
BlackRock
New York
-$7.3M
3
LOAMS
Lombard Odier Asset Management (Switzerland)
Switzerland
-$6.5M
4
FCM
Frontier Capital Management
Massachusetts
-$2.99M
5
CSS
Cubist Systematic Strategies
Connecticut
-$2.96M
Name Holding Trade Value Shares
Change 		Shares
Change %
Nisa Investment Advisors
126
Nisa Investment Advisors
Missouri
$6K – – –
IC
127
Ikarian Capital
Texas
$6K +$327 +3 +6%
MCC
128
Money Concepts Capital
Florida
$6K +$6K +58 New
AF
129
Advisornet Financial
Minnesota
$5K – – –
PHK
130
Point72 Hong Kong
Hong Kong
$3K -$5.13K -53 -63%
Macquarie Group
131
Macquarie Group
Australia
$2.82K – – –
KFS
132
Kelly Financial Services
Massachusetts
$1.84K – – –
QCG
133
Quadrant Capital Group
Ohio
$1K -$3.83K -23 -79%
AF
134
Allworth Financial
California
$1K – – –
Daiwa Securities Group
135
Daiwa Securities Group
Japan
$1K – – –
JG
136
Jefferies Group
New York
$737 +$737 +7 New
APA
137
American Portfolios Advisors
New York
$612 -$6.22K -61 -91%
Alkeon Capital Management
138
Alkeon Capital Management
New York
– -$12.6M -130,773 Closed
JGC
139
J. Goldman & Co
New York
– -$1.76M -18,283 Closed
Jennison Associates
140
Jennison Associates
New York
– -$1.74M -18,050 Closed
HF
141
HRT Financial
New York
– -$1.6M -16,555 Closed
Tudor Investment Corp
142
Tudor Investment Corp
Connecticut
– -$1.34M -13,902 Closed
GCP
143
GSA Capital Partners
United Kingdom
– -$1.23M -12,798 Closed
Squarepoint
144
Squarepoint
New York
– -$799K -8,285 Closed
Group One Trading
145
Group One Trading
Illinois
– -$772K -8,008 Closed
JF
146
Jump Financial
Illinois
– -$551K -5,708 Closed
AG
147
Algert Global
California
– -$503K -5,216 Closed
DTL
148
Dynamic Technology Lab
Singapore
– -$392K -4,070 Closed
Simplex Trading
149
Simplex Trading
Illinois
– -$377K -3,916 Closed
VRS
150
Virginia Retirement Systems
Virginia
– -$277 -2,873 Closed
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