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Karyopharm Therapeutics

118 hedge funds and large institutions have $103M invested in Karyopharm Therapeutics in 2023 Q3 according to their latest regulatory filings, with 16 funds opening new positions, 40 increasing their positions, 29 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

331% more call options, than puts

Call options by funds: $785K | Put options by funds: $182K

38% more repeat investments, than reductions

Existing positions increased: 40 | Existing positions reduced: 29

0.27% less ownership

Funds ownership: 4.77%4.5% (-0.27%)

14% less funds holding

Funds holding: 137118 (-19)

29% less capital invested

Capital invested by funds: $145M → $103M (-$42.2M)

54% less first-time investments, than exits

New positions opened: 16 | Existing positions closed: 35

Holders
118
Holders Change
-19
Holders Change %
-13.87%
% of All Funds
1.87%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
16
Increased
40
Reduced
29
Closed
35
Calls
$785K
Puts
$182K
Net Calls
+$603K
Net Calls Change
+$232K
Name Holding Trade Value Shares
Change
Change in
Stake
Janney Montgomery Scott
101
Janney Montgomery Scott
Pennsylvania
$13K
Osaic Holdings
102
Osaic Holdings
Arizona
$9.3K -$202 -9 -2%
MLICM
103
Metropolitan Life Insurance Company (MetLife)
New York
$8.36K
AIP
104
Ameritas Investment Partners
Nebraska
$8.3K
PI
105
PEAK6 Investments
Illinois
$6.1K
PNC Financial Services Group
106
PNC Financial Services Group
Pennsylvania
$4.02K
CUAMC
107
China Universal Asset Management Company
China
$3.92K +$2.13K +95 +95%
FCMT
108
Founders Capital Management (Texas)
Texas
$2.68K
TWC
109
TD Waterhouse Canada
Ontario, Canada
$2.49K +$1.48K +66 +93%
Citigroup
110
Citigroup
New York
$2.15K -$54.8K -2,443 -96%
MLA
111
MB, Levis & Associates
Pennsylvania
$2.01K
HI
112
Harbour Investments
Wisconsin
$1.74K
Nisa Investment Advisors
113
Nisa Investment Advisors
Missouri
$1.07K
AF
114
Advisornet Financial
Minnesota
$938
AF
115
Allworth Financial
California
$670
Point72 Asset Management
116
Point72 Asset Management
Connecticut
$364 +$404 +18 New
KFS
117
Kelly Financial Services
Massachusetts
$335
Zurich Cantonal Bank
118
Zurich Cantonal Bank
Switzerland
$8 -$27.1K -1,209 Closed
FGAM
119
Financial Gravity Asset Management
Texas
$2
OM
120
Opaleye Management
Massachusetts
-$3.2M -119,000 Closed
RCMNY
121
Rubric Capital Management (New York)
New York
-$1.65M -61,280 Closed
Qube Research & Technologies (QRT)
122
Qube Research & Technologies (QRT)
United Kingdom
-$1.26M -46,871 Closed
Jane Street
123
Jane Street
New York
-$1.19M -44,158 Closed
Wellington Management Group
124
Wellington Management Group
Massachusetts
-$1.01M -37,453 Closed
PIM
125
Platinum Investment Management
Australia
-$895K -33,333 Closed

KPTI Hedge Fund Activity: Q3 2023 in Review

118 of the 6,301 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q3 2023, worth a combined $103M — down 29% from $145M a quarter earlier.

Sellers outnumbered buyers: 35 funds closed out of KPTI and 16 opened new positions — a net loss of 19 holders — while 29 trimmed existing stakes and 40 added.

The largest buyer was Jacobs Levy Equity Management, adding an estimated $2.51M. The largest seller was Opaleye Management, exiting entirely with an estimated $3.2M sold.

  • 118 institutional investors held Karyopharm Therapeutics (KPTI) as of Q3 2023, down from 137 in Q2 2023.
  • Funds reported $103M of Karyopharm Therapeutics stock for Q3 2023, down 29% quarter-over-quarter.
  • 16 funds opened new Karyopharm Therapeutics positions in Q3 2023 and 35 closed out, a net change of -19 holders.
  • The largest Karyopharm Therapeutics buyer in Q3 2023 was Jacobs Levy Equity Management, an estimated $2.51M added.
  • The largest Karyopharm Therapeutics seller in Q3 2023 was Opaleye Management, an estimated $3.2M sold.

Based on aggregated 13F filings for Q3 2023.