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Karyopharm Therapeutics
KPTI

Overview Fund Activity

154 hedge funds and large institutions have $334M invested in Karyopharm Therapeutics in 2022 Q4 according to their latest regulatory filings, with 32 funds opening new positions, 63 increasing their positions, 39 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
154
Holders Change
+7
Holders Change %
+4.76%
% of All Funds
2.48%
Holding in Top 10
–
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
–
New
32
Increased
63
Reduced
39
Closed
24
Calls
$1.83M
Puts
$1.12M
Net Calls
+$703K
Net Calls Change
-$761K

Top Buyers

1
APM
Avidity Partners Management
Texas
$32.8M
2
RCMNY
Rubric Capital Management (New York)
New York
$28.2M
3
AC
Armistice Capital
New York
$13.1M
4
Marshall Wace
Marshall Wace
United Kingdom
$7.51M
5
Point72 Asset Management
Point72 Asset Management
Connecticut
$6.77M

Top Sellers

1
RHJA
Rice Hall James & Associates
California
$0
2
ACM
Altium Capital Management
New York
$0
3
FCM
Frontier Capital Management
Massachusetts
$0
4
LOAMS
Lombard Odier Asset Management (Switzerland)
Switzerland
$0
5
State Street
State Street
Massachusetts
$28.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
Allspring Global Investments
101
Allspring Global Investments
North Carolina
$90.4K -$33.8K -662 -27%
ACM
102
Aquatic Capital Management
Illinois
$86K -$66.7K -1,314 -44%
WMSA
103
Weiss Multi-Strategy Advisers
New York
$82K -$1.99K -39 -2%
DCM
104
Dupont Capital Management
Delaware
$78.1K +$78.1K +1,530 New
Franklin Resources
105
Franklin Resources
California
$70.2K – – –
TRCT
106
Tower Research Capital (TRC)
New York
$69K -$49K -952 -42%
ASRS
107
Arizona State Retirement System
Arizona
$68.9K +$2.86K +56 +4%
Baird Financial Group
108
Baird Financial Group
Wisconsin
$65K +$3.06K +60 +5%
Simplex Trading
109
Simplex Trading
Illinois
$59K +$39.3K +772 +199%
SOW
110
State of Wyoming
Wyoming
$58.1K +$38K +745 +189%
AGM
111
Alpine Global Management
New York
$58K +$58K +1,139 New
ProShare Advisors
112
ProShare Advisors
Maryland
$56.9K +$5.51K +108 +11%
Mackenzie Financial
113
Mackenzie Financial
Ontario, Canada
$53.8K +$6.84K +134 +15%
YIH
114
Y-Intercept (HK)
Hong Kong
$51.3K +$16.1K +315 +46%
ATPW
115
Ashton Thomas Private Wealth
Arizona
$49.3K +$49.3K +967 New
SCA
116
Snowden Capital Advisors
New York
$48.4K +$6.94K +136 +17%
Prudential Financial
117
Prudential Financial
New Jersey
$46.9K -$60.8K -1,193 -56%
E
118
Ergoteles
New York
$45.3K +$45.3K +888 New
Mercer Global Advisors
119
Mercer Global Advisors
Colorado
$42K +$2.73K +53 +7%
Balyasny Asset Management
120
Balyasny Asset Management
Illinois
$41.6K -$1.98M -38,887 -98%
Janus Henderson Group
121
Janus Henderson Group
United Kingdom
$41.5K -$41.5K -813 -50%
MC
122
Moors & Cabot
Massachusetts
$41.5K -$30.5K -597 -42%
AB
123
Amalgamated Bank
New York
$41K – – –
Zurich Cantonal Bank
124
Zurich Cantonal Bank
Switzerland
$40.9K +$5.51K +108 +16%
Creative Planning
125
Creative Planning
Kansas
$39.4K – – –
3 4
5
6 7