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Karyopharm Therapeutics
KPTI

Overview Fund Activity

87 hedge funds and large institutions have $41.2M invested in Karyopharm Therapeutics in 2024 Q4 according to their latest regulatory filings, with 14 funds opening new positions, 21 increasing their positions, 23 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
87
Holders Change
-4
Holders Change %
-4.4%
% of All Funds
1.16%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
14
Increased
21
Reduced
23
Closed
18
Calls
$196K
Puts
$47K
Net Calls
+$149K
Net Calls Change
-$712K

Top Buyers

1
Morgan Stanley
Morgan Stanley
New York
$2.38M
2
Adage Capital Partners
Adage Capital Partners
Massachusetts
$4.27M
3
Jane Street
Jane Street
New York
$506K
4
Susquehanna International Group
Susquehanna International Group
Pennsylvania
$449K
5
Marshall Wace
Marshall Wace
United Kingdom
$1.63M

Top Sellers

1
EP
Eversept Partners
New York
$1.41M
2
AA
AlphaCentric Advisors
Puerto Rico
$0
3
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
$187K
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
$155K
5
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
$889K
Name Holding Trade Value Shares
Change 		Shares
Change %
Osaic Holdings
76
Osaic Holdings
Arizona
$3.66K +$673 +66 +23%
QC
77
Quent Capital
New York
$2.36K – – –
VWA
78
VSM Wealth Advisory
Maryland
$1.35K +$1.35K +133 New
MLA
79
MB, Levis & Associates
Pennsylvania
$1.01K – – –
HI
80
Harbour Investments
Wisconsin
$879 – – –
AWM
81
Activest Wealth Management
Florida
$676 – – –
SS
82
SBI Securities
Japan
$485 +$485 +48 New
Wells Fargo
83
Wells Fargo
California
$450 – – –
AF
84
Allworth Financial
California
$334 – – –
BGAI
85
Bruce G. Allen Investments
Colorado
$229 – – –
CIBC Private Wealth Group
86
CIBC Private Wealth Group
Georgia
$36 – – –
WBC
87
West Branch Capital
Massachusetts
$33 – – –
AA
88
AlphaCentric Advisors
Puerto Rico
– -$934K -75,000 Closed
DCM
89
DAFNA Capital Management
California
– -$160K -12,845 Closed
MIM
90
Monashee Investment Management
Massachusetts
– -$25.6K -8,829 Closed
Qube Research & Technologies (QRT)
91
Qube Research & Technologies (QRT)
United Kingdom
– -$51.5K -4,135 Closed
Invesco
92
Invesco
Georgia
– -$48.3K -3,877 Closed
Cerity Partners
93
Cerity Partners
New York
– -$42.8K -3,436 Closed
CFM
94
Catalyst Funds Management
Australia
– -$23.7K -1,907 Closed
XT
95
XTX Topco
Cayman Islands
– -$21.5K -1,727 Closed
VPIM
96
Vanguard Personalized Indexing Management
California
– -$14.3K -1,146 Closed
Victory Capital Management
97
Victory Capital Management
Texas
– -$12K -966 Closed
AQR Capital Management
98
AQR Capital Management
Connecticut
– -$10.1K -815 Closed
AWE
99
Avidian Wealth Enterprises
Texas
– -$8.38K -673 Closed
PNC Financial Services Group
100
PNC Financial Services Group
Pennsylvania
– -$2.49K -200 Closed
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