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Karyopharm Therapeutics
KPTI

Overview Fund Activity

154 hedge funds and large institutions have $334M invested in Karyopharm Therapeutics in 2022 Q4 according to their latest regulatory filings, with 32 funds opening new positions, 63 increasing their positions, 39 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
154
Holders Change
+7
Holders Change %
+4.76%
% of All Funds
2.48%
Holding in Top 10
–
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
–
New
32
Increased
63
Reduced
39
Closed
24
Calls
$1.83M
Puts
$1.12M
Net Calls
+$703K
Net Calls Change
-$761K

Top Buyers

1
APM
Avidity Partners Management
Texas
$32.8M
2
RCMNY
Rubric Capital Management (New York)
New York
$28.2M
3
AC
Armistice Capital
New York
$13.1M
4
Marshall Wace
Marshall Wace
United Kingdom
$7.51M
5
Point72 Asset Management
Point72 Asset Management
Connecticut
$6.77M

Top Sellers

1
RHJA
Rice Hall James & Associates
California
$0
2
ACM
Altium Capital Management
New York
$0
3
FCM
Frontier Capital Management
Massachusetts
$0
4
LOAMS
Lombard Odier Asset Management (Switzerland)
Switzerland
$0
5
State Street
State Street
Massachusetts
$28.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
Royal Bank of Canada
76
Royal Bank of Canada
Ontario, Canada
$218K +$180K +3,537 +475%
AQR Capital Management
77
AQR Capital Management
Connecticut
$210K -$173K -3,402 -45%
PCM
78
Prelude Capital Management
New York
$199K +$153K +3,003 +334%
JF
79
Jump Financial
Illinois
$199K +$199K +3,898 New
T. Rowe Price Associates
80
T. Rowe Price Associates
Maryland
$197K +$18.5K +362 +10%
Principal Financial Group
81
Principal Financial Group
Iowa
$193K +$126K +2,465 +186%
Squarepoint
82
Squarepoint
New York
$178K +$178K +3,486 New
EGM
83
Engineers Gate Manager
New York
$168K +$63.8K +1,250 +61%
New York State Common Retirement Fund
84
New York State Common Retirement Fund
New York
$167K -$62.4K -1,222 -27%
PMEF
85
Point72 Middle East FZE
United Arab Emirates
$161K +$161K +3,150 New
Legal & General Group
86
Legal & General Group
United Kingdom
$156K +$27.3K +534 +21%
MAM
87
Martingale Asset Management
Massachusetts
$154K +$154K +3,021 New
BCM
88
Bayesian Capital Management
New York
$148K +$148K +2,909 New
Federated Hermes
89
Federated Hermes
Pennsylvania
$131K +$131K +2,574 New
AIG
90
American International Group
New York
$125K +$2.24K +44 +2%
EFM
91
E Fund Management
China
$124K -$32K -628 -21%
Invesco
92
Invesco
Georgia
$123K +$4.13K +81 +3%
RWMG
93
Redwood Wealth Management Group
New Jersey
$113K +$113K +2,215 New
OQS
94
Occudo Quantitative Strategies
Florida
$101K +$101K +1,988 New
MIM
95
MetLife Investment Management
New Jersey
$99.9K -$40.8K -801 -29%
VOYA Investment Management
96
VOYA Investment Management
Georgia
$98.1K -$485K -9,517 -83%
FRM
97
Fox Run Management
Connecticut
$98K +$98K +1,922 New
Manulife (Manufacturers Life Insurance)
98
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$97.8K -$918 -18 -0.9%
Teacher Retirement System of Texas
99
Teacher Retirement System of Texas
Texas
$97K +$17.7K +348 +22%
State Board of Administration of Florida Retirement System
100
State Board of Administration of Florida Retirement System
Florida
$91.9K -$88.6K -1,737 -49%
2 3
4
5 6