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Karyopharm Therapeutics

134 hedge funds and large institutions have $334M invested in Karyopharm Therapeutics in 2021 Q3 according to their latest regulatory filings, with 14 funds opening new positions, 58 increasing their positions, 34 reducing their positions, and 33 closing their positions.

New
Increased
Maintained
Reduced
Closed

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more funds holding in top 10

Funds holding in top 10:

less ownership

Funds ownership:

less funds holding

Funds holding:

45% less capital invested

Capital invested by funds: $608M → $334M (-$273M)

58% less first-time investments, than exits

New positions opened: 14 | Existing positions closed: 33

72% less call options, than puts

Call options by funds: $2.28M | Put options by funds: $8.13M

Holders
134
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$2.28M
Puts
$8.13M
Net Calls
Net Calls Change

Top Buyers

1 +$12.8M
2 +$2.78M
3 +$1.83M
4
Two Sigma Investments
Two Sigma Investments
New York
+$1.46M
5
Morgan Stanley
Morgan Stanley
New York
+$1.46M

Top Sellers

1 -$8.28M
2 -$7.55M
3 -$6.15M
4
JGC
J. Goldman & Co
New York
-$5.51M
5
AAM
AMI Asset Management
California
-$5.31M
Name Holding Trade Value Shares
Change
Change in
Stake
76
$174K
77
$174K
78
$172K
79
$165K
80
$155K
81
$152K
82
$148K
83
$148K
84
$146K
85
$137K
86
$124K
87
$123K
88
$122K
89
$122K
90
$119K
91
$103K
92
$102K
93
$101K
94
$95K
95
$95K
96
$94K
97
$81K
98
$79K
99
$78K
100
$76K