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Karyopharm Therapeutics
KPTI

Overview Fund Activity

153 hedge funds and large institutions have $608M invested in Karyopharm Therapeutics in 2021 Q2 according to their latest regulatory filings, with 21 funds opening new positions, 54 increasing their positions, 56 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
153
Holders Change
-18
Holders Change %
-10.53%
% of All Funds
2.67%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
21
Increased
54
Reduced
56
Closed
38
Calls
$4.62M
Puts
$14.1M
Net Calls
-$9.52M
Net Calls Change
-$8.17M

Top Buyers

1
RCMNY
Rubric Capital Management (New York)
New York
+$43.9M
2
BlackRock
BlackRock
New York
+$10.6M
3
LOAMS
Lombard Odier Asset Management (Switzerland)
Switzerland
+$5.64M
4
State Street
State Street
Massachusetts
+$5M
5
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
+$3.96M

Top Sellers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$14.2M
2
Wellington Management Group
Wellington Management Group
Massachusetts
-$13.6M
3
LCM
Laurion Capital Management
New York
-$9.49M
4
CLOS
Compagnie Lombard Odier SCmA
Switzerland
-$8.73M
5
Two Sigma Investments
Two Sigma Investments
New York
-$6.67M
Name Holding Trade Value Shares
Change 		Shares
Change %
VOYA Investment Management
76
VOYA Investment Management
Georgia
$304K -$24.8K -160 -8%
GCP
77
GSA Capital Partners
United Kingdom
$301K -$14.9K -96 -5%
Principal Financial Group
78
Principal Financial Group
Iowa
$297K -$33.2K -214 -10%
Invesco
79
Invesco
Georgia
$295K +$108K +695 +57%
ECM
80
ExodusPoint Capital Management
New York
$280K +$12.5K +81 +5%
Jane Street
81
Jane Street
New York
$278K -$479K -3,092 -63%
TI
82
Trexquant Investment
Connecticut
$253K -$99.1K -641 -28%
KFS
83
Kelly Financial Services
Massachusetts
$250K +$225K +155 +912%
Dimensional Fund Advisors
84
Dimensional Fund Advisors
Texas
$249K -$1.27M -8,168 -84%
MIM
85
MetLife Investment Management
New Jersey
$245K – – –
VRS
86
Virginia Retirement Systems
Virginia
$243K +$243K +1,567 New
BFM
87
Boothbay Fund Management
New York
$238K +$238K +1,538 New
JPMPWA
88
J.P. Morgan Private Wealth Advisors
California
$232K +$49.6K +320 +27%
MLICM
89
Metropolitan Life Insurance Company (MetLife)
New York
$230K +$29.7K +192 +15%
GSEP
90
Golden State Equity Partners
California
$228K +$118K +761 +107%
SCM
91
Symons Capital Management
Pennsylvania
$225K -$1.24K -8 -0.5%
Royal Bank of Canada
92
Royal Bank of Canada
Ontario, Canada
$224K +$107K +691 +91%
PCM
93
Prelude Capital Management
New York
$217K – – –
CC
94
Centiva Capital
New York
$211K +$211K +1,360 New
MC
95
Moors & Cabot
Massachusetts
$192K -$3.09K -20 -2%
Renaissance Technologies
96
Renaissance Technologies
New York
$191K +$191K +1,231 New
Legal & General Group
97
Legal & General Group
United Kingdom
$190K -$8.71K -56 -4%
VF
98
Virtu Financial
New York
$188K -$297K -1,922 -61%
Baird Financial Group
99
Baird Financial Group
Wisconsin
$175K +$13.9K +90 +9%
ASRS
100
Arizona State Retirement System
Arizona
$167K +$12.7K +82 +8%
2 3
4
5 6