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Karyopharm Therapeutics

157 hedge funds and large institutions have $949M invested in Karyopharm Therapeutics in 2020 Q3 according to their latest regulatory filings, with 29 funds opening new positions, 55 increasing their positions, 53 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

61% more call options, than puts

Call options by funds: $7.81M | Put options by funds: $4.85M

1% more funds holding

Funds holding: 155157 (+2)

7% more first-time investments, than exits

New positions opened: 29 | Existing positions closed: 27

4% more repeat investments, than reductions

Existing positions increased: 55 | Existing positions reduced: 53

0.45% less ownership

Funds ownership: 6.36%5.91% (-0.45%)

28% less capital invested

Capital invested by funds: $1.32B → $949M (-$372M)

50% less funds holding in top 10

Funds holding in top 10: 42 (-2)

Holders
157
Holders Change
+2
Holders Change %
+1.29%
% of All Funds
3.17%
Holding in Top 10
2
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-50%
% of All Funds
0.04%
New
29
Increased
55
Reduced
53
Closed
27
Calls
$7.81M
Puts
$4.85M
Net Calls
+$2.96M
Net Calls Change
-$5.5M
Name Holding Trade Value Shares
Change
Change in
Stake
Manulife (Manufacturers Life Insurance)
76
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$578K -$12K -49 -2%
EGM
77
Engineers Gate Manager
New York
$550K +$402K +1,643 +189%
SEI Investments
78
SEI Investments
Pennsylvania
$515K -$18.6K -76 -3%
DekaBank Deutsche Girozentrale
79
DekaBank Deutsche Girozentrale
Germany
$515K +$590K +2,413 New
VEA
80
Virtus ETF Advisers
New York
$511K +$47.9K +196 +9%
Tudor Investment Corp
81
Tudor Investment Corp
Connecticut
$473K +$529K +2,161 New
Qube Research & Technologies (QRT)
82
Qube Research & Technologies (QRT)
United Kingdom
$473K +$529K +2,162 New
MIM
83
MetLife Investment Management
New Jersey
$460K
VOYA Investment Management
84
VOYA Investment Management
Georgia
$458K +$116K +473 +29%
TD Asset Management
85
TD Asset Management
Ontario, Canada
$425K -$403K -1,647 -46%
TC
86
TwinBeech Capital
New York
$425K +$475K +1,942 New
QI
87
QS Investors
New York
$422K -$1.91M -7,810 -80%
State Board of Administration of Florida Retirement System
88
State Board of Administration of Florida Retirement System
Florida
$385K
TRSOTSOK
89
Teachers Retirement System of the State of Kentucky
Kentucky
$378K
SFI
90
Susquehanna Fundamental Investments
Pennsylvania
$371K +$414K +1,694 New
Principal Financial Group
91
Principal Financial Group
Iowa
$344K -$26.4K -108 -6%
Osaic Holdings
92
Osaic Holdings
Arizona
$340K -$31.1K -127 -8%
ECM
93
ExodusPoint Capital Management
New York
$331K +$370K +1,513 New
Group One Trading
94
Group One Trading
Illinois
$327K +$366K +1,495 New
WMSA
95
Weiss Multi-Strategy Advisers
New York
$323K +$361K +1,476 New
Axa
96
Axa
France
$321K -$510K -2,086 -59%
JMPWA
97
JP Morgan Private Wealth Advisors
California
$320K +$114K +467 +47%
MLICM
98
Metropolitan Life Insurance Company (MetLife)
New York
$317K
ProShare Advisors
99
ProShare Advisors
Maryland
$298K -$13K -53 -4%
ACM
100
AlphaCrest Capital Management
New York
$295K +$329K +1,347 New

KPTI Hedge Fund Activity: Q3 2020 in Review

157 of the 4,956 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q3 2020, worth a combined $949M — down 28% from $1.32B a quarter earlier.

Buyers outnumbered sellers: 29 funds opened new KPTI positions and 27 closed out — a net gain of 2 holders — while 55 added to existing stakes and 53 trimmed.

The largest buyer was Two Sigma Investments, adding an estimated $17.2M. The largest seller was Consonance Capital Management, exiting entirely with an estimated $123M sold.

  • 157 institutional investors held Karyopharm Therapeutics (KPTI) as of Q3 2020, up from 155 in Q2 2020.
  • Funds reported $949M of Karyopharm Therapeutics stock for Q3 2020, down 28% quarter-over-quarter.
  • 29 funds opened new Karyopharm Therapeutics positions in Q3 2020 and 27 closed out, a net change of +2 holders.
  • The largest Karyopharm Therapeutics buyer in Q3 2020 was Two Sigma Investments, an estimated $17.2M added.
  • The largest Karyopharm Therapeutics seller in Q3 2020 was Consonance Capital Management, an estimated $123M sold.

Based on aggregated 13F filings for Q3 2020.