Karyopharm Therapeutics
KPTI
KPTI
52 hedge funds and large institutions have $19.5M invested in Karyopharm Therapeutics in 2025 Q3 according to their latest regulatory filings, with 7 funds opening new positions, 7 increasing their positions, 20 reducing their positions, and 5 closing their positions.
New
Increased
Maintained
Reduced
Closed
more first-time investments, than exits
New positions opened: | Existing positions closed:
more funds holding
Funds holding: →
more capital invested
Capital invested by funds: $ → $
less ownership
Funds ownership: →
26% less call options, than puts
Call options by funds: $5.74M | Put options by funds: $7.74M
65% less repeat investments, than reductions
Existing positions increased: 7 | Existing positions reduced: 20
Holders
52
Holding in Top 10
–
Calls
$5.74M
Puts
$7.74M
Top Buyers
| 1 | +$190K | |
| 2 | +$135K | |
| 3 | +$82.9K | |
| 4 |
Belvedere Trading
Chicago,
Illinois
|
+$78.4K |
| 5 |
State Street
Boston,
Massachusetts
|
+$70.2K |
Top Sellers
| 1 | -$1.38M | |
| 2 | -$1.11M | |
| 3 | -$1.11M | |
| 4 |
Bank of America
Charlotte,
North Carolina
|
-$906K |
| 5 |
PAI
Palo Alto Investors
Palo Alto,
California
|
-$810K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
51
CIBC Private Wealth Group
Atlanta,
Georgia
| $20 |
|
|||
|
PAI
52
Pittenger & Anderson Inc
Lincoin,
Nebraska
| $20 |
|
|||
|
EP
53
Eversept Partners
New York
| – |
|
|||
54
Citadel Advisors
Miami,
Florida
| – |
|
|||
|
PAI
55
Palo Alto Investors
Palo Alto,
California
| – |
|
|||
56
Millennium Management
New York
| – |
|
|||
57
Raymond James Financial
St Petersburg,
Florida
| – |
|