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Karyopharm Therapeutics
KPTI

Overview Fund Activity

87 hedge funds and large institutions have $41.2M invested in Karyopharm Therapeutics in 2024 Q4 according to their latest regulatory filings, with 14 funds opening new positions, 21 increasing their positions, 23 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
87
Holders Change
-4
Holders Change %
-4.4%
% of All Funds
1.16%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
14
Increased
21
Reduced
23
Closed
18
Calls
$196K
Puts
$47K
Net Calls
+$149K
Net Calls Change
-$712K

Top Buyers

1
Morgan Stanley
Morgan Stanley
New York
$2.38M
2
Adage Capital Partners
Adage Capital Partners
Massachusetts
$4.27M
3
Jane Street
Jane Street
New York
$506K
4
Susquehanna International Group
Susquehanna International Group
Pennsylvania
$449K
5
Marshall Wace
Marshall Wace
United Kingdom
$1.63M

Top Sellers

1
EP
Eversept Partners
New York
$1.41M
2
AA
AlphaCentric Advisors
Puerto Rico
$0
3
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
$187K
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
$155K
5
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
$889K
Name Holding Trade Value Shares
Change 		Shares
Change %
T. Rowe Price Associates
51
T. Rowe Price Associates
Maryland
$44K -$48.2K -4,693 -52%
Charles Schwab
52
Charles Schwab
California
$34.6K +$122 +12 +0.4%
TWC
53
TD Waterhouse Canada
Ontario, Canada
$32.2K +$32.2K +3,203 New
Focus Partners Wealth
54
Focus Partners Wealth
Massachusetts
$31K +$31K +3,055 New
Baird Financial Group
55
Baird Financial Group
Wisconsin
$30.3K +$4.74K +467 +19%
VCIM
56
Velan Capital Investment Management
Georgia
$27.1K +$27.1K +2,667 New
HSBC Holdings
57
HSBC Holdings
United Kingdom
$26.5K – – –
FIM
58
Freedom Investment Management
Connecticut
$26.2K +$1K +99 +4%
KIG
59
Kennedy Investment Group
New Jersey
$23.7K – – –
RS
60
R Squared
Hong Kong
$20.1K +$20.1K +1,978 New
EGM
61
Engineers Gate Manager
New York
$19.4K -$13.1K -1,296 -40%
Commonwealth Equity Services
62
Commonwealth Equity Services
Massachusetts
$15K +$61 +6 +0.4%
Squarepoint
63
Squarepoint
New York
$14.1K +$14.1K +1,386 New
Corient Private Wealth
64
Corient Private Wealth
Florida
$13.9K -$396 -39 -3%
ACM
65
ADAR1 Capital Management
Texas
$13.5K +$13.5K +1,333 New
EM
66
ELCO Management
New York
$10.9K – – –
WAG
67
Winthrop Advisory Group
Massachusetts
$10.1K – – –
CG
68
Caprock Group
Idaho
$7.85K +$7.85K +773 New
SCA
69
Snowden Capital Advisors
New York
$7.44K – – –
Wolverine Trading
70
Wolverine Trading
Illinois
$7.19K -$2.43K -231 -25%
Walleye Capital
71
Walleye Capital
New York
$7.07K +$7.07K +697 New
Janney Montgomery Scott
72
Janney Montgomery Scott
Pennsylvania
$7K – – –
BBA
73
BLB&B Advisors
Pennsylvania
$6.86K – – –
TRCT
74
Tower Research Capital (TRC)
New York
$5.2K +$5.2K +513 New
Royal Bank of Canada
75
Royal Bank of Canada
Ontario, Canada
$4K -$896 -97 -18%
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3
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