We are live on ! Find out more
KPTI icon

Karyopharm Therapeutics

118 hedge funds and large institutions have $103M invested in Karyopharm Therapeutics in 2023 Q3 according to their latest regulatory filings, with 16 funds opening new positions, 40 increasing their positions, 29 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

331% more call options, than puts

Call options by funds: $785K | Put options by funds: $182K

38% more repeat investments, than reductions

Existing positions increased: 40 | Existing positions reduced: 29

0.27% less ownership

Funds ownership: 4.77%4.5% (-0.27%)

14% less funds holding

Funds holding: 137118 (-19)

29% less capital invested

Capital invested by funds: $145M → $103M (-$42.2M)

54% less first-time investments, than exits

New positions opened: 16 | Existing positions closed: 35

Holders
118
Holders Change
-19
Holders Change %
-13.87%
% of All Funds
1.87%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
16
Increased
40
Reduced
29
Closed
35
Calls
$785K
Puts
$182K
Net Calls
+$603K
Net Calls Change
+$232K
Name Holding Trade Value Shares
Change
Change in
Stake
PMEF
51
Point72 Middle East FZE
United Arab Emirates
$127K +$13.8K +614 +11%
Russell Investments Group
52
Russell Investments Group
United Kingdom
$127K -$898 -40 -0.6%
T. Rowe Price Associates
53
T. Rowe Price Associates
Maryland
$117K +$28.4K +1,267 +28%
ETC
54
Exchange Traded Concepts
Oklahoma
$116K +$30K +1,338 +30%
AA
55
ALPS Advisors
Colorado
$113K +$943 +42 +0.8%
GCM
56
Graham Capital Management
Connecticut
$110K +$29.8K +1,326 +32%
BFM
57
Boothbay Fund Management
New York
$110K
Royal Bank of Canada
58
Royal Bank of Canada
Ontario, Canada
$104K -$22 -1 -0%
Invesco
59
Invesco
Georgia
$85.5K +$13.9K +618 +17%
MIM
60
MetLife Investment Management
New Jersey
$80.7K
Deutsche Bank
61
Deutsche Bank
Germany
$78K -$2.3M -102,330 -96%
AIG
62
American International Group
New York
$75.7K +$3.01K +134 +4%
Group One Trading
63
Group One Trading
Illinois
$73K +$79.3K +3,534 +3,534%
Manulife (Manufacturers Life Insurance)
64
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$63.1K
CC
65
Centiva Capital
New York
$61.4K +$19.6K +873 +40%
VOYA Investment Management
66
VOYA Investment Management
Georgia
$60.9K
HSBC Holdings
67
HSBC Holdings
United Kingdom
$60.4K +$48.8K +2,176 +266%
GW
68
GW & Wade
Massachusetts
$60K +$67.5K +3,009 New
SOW
69
State of Wyoming
Wyoming
$54.6K +$61K +2,716 New
EGM
70
Engineers Gate Manager
New York
$52.2K +$37.5K +1,669 +180%
Connor, Clark & Lunn Investment Management (CC&L)
71
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$47.3K -$3.3K -147 -6%
Two Sigma Advisers
72
Two Sigma Advisers
New York
$47.2K -$337K -15,000 -86%
KIG
73
Kennedy Investment Group
New Jersey
$46.9K
Squarepoint
74
Squarepoint
New York
$45.8K +$51.1K +2,277 New
Principal Financial Group
75
Principal Financial Group
Iowa
$44K

KPTI Hedge Fund Activity: Q3 2023 in Review

118 of the 6,301 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q3 2023, worth a combined $103M — down 29% from $145M a quarter earlier.

Sellers outnumbered buyers: 35 funds closed out of KPTI and 16 opened new positions — a net loss of 19 holders — while 29 trimmed existing stakes and 40 added.

The largest buyer was Jacobs Levy Equity Management, adding an estimated $2.51M. The largest seller was Opaleye Management, exiting entirely with an estimated $3.2M sold.

  • 118 institutional investors held Karyopharm Therapeutics (KPTI) as of Q3 2023, down from 137 in Q2 2023.
  • Funds reported $103M of Karyopharm Therapeutics stock for Q3 2023, down 29% quarter-over-quarter.
  • 16 funds opened new Karyopharm Therapeutics positions in Q3 2023 and 35 closed out, a net change of -19 holders.
  • The largest Karyopharm Therapeutics buyer in Q3 2023 was Jacobs Levy Equity Management, an estimated $2.51M added.
  • The largest Karyopharm Therapeutics seller in Q3 2023 was Opaleye Management, an estimated $3.2M sold.

Based on aggregated 13F filings for Q3 2023.