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Karyopharm Therapeutics
KPTI

Overview Fund Activity

154 hedge funds and large institutions have $334M invested in Karyopharm Therapeutics in 2022 Q4 according to their latest regulatory filings, with 32 funds opening new positions, 63 increasing their positions, 39 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
154
Holders Change
+7
Holders Change %
+4.76%
% of All Funds
2.48%
Holding in Top 10
–
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
–
New
32
Increased
63
Reduced
39
Closed
24
Calls
$1.83M
Puts
$1.12M
Net Calls
+$703K
Net Calls Change
-$761K

Top Buyers

1
APM
Avidity Partners Management
Texas
$32.8M
2
RCMNY
Rubric Capital Management (New York)
New York
$28.2M
3
AC
Armistice Capital
New York
$13.1M
4
Marshall Wace
Marshall Wace
United Kingdom
$7.51M
5
Point72 Asset Management
Point72 Asset Management
Connecticut
$6.77M

Top Sellers

1
RHJA
Rice Hall James & Associates
California
$0
2
ACM
Altium Capital Management
New York
$0
3
FCM
Frontier Capital Management
Massachusetts
$0
4
LOAMS
Lombard Odier Asset Management (Switzerland)
Switzerland
$0
5
State Street
State Street
Massachusetts
$28.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
Susquehanna International Group
51
Susquehanna International Group
Pennsylvania
$868K -$465K -9,115 -35%
PI
52
Putnam Investments
Massachusetts
$825K +$825K +16,175 New
Wellington Management Group
53
Wellington Management Group
Massachusetts
$777K -$56.2K -1,101 -7%
Charles Schwab
54
Charles Schwab
California
$703K +$21.5K +422 +3%
DCM
55
DAFNA Capital Management
California
$655K +$655K +12,845 New
Renaissance Technologies
56
Renaissance Technologies
New York
$644K -$405K -7,933 -39%
Ameriprise
57
Ameriprise
Minnesota
$560K -$17.1K -336 -3%
Walleye Capital
58
Walleye Capital
New York
$544K -$1.75M -34,237 -76%
AllianceBernstein
59
AllianceBernstein
Tennessee
$537K +$67.6K +1,326 +14%
Russell Investments Group
60
Russell Investments Group
United Kingdom
$497K +$56.9K +1,116 +13%
HWAM
61
Hennion & Walsh Asset Management
New Jersey
$491K -$449K -8,804 -48%
CS
62
Credit Suisse
Switzerland
$483K +$9.49K +186 +2%
XT
63
XTX Topco
Cayman Islands
$445K +$307K +6,018 +223%
California State Teachers Retirement System (CalSTRS)
64
California State Teachers Retirement System (CalSTRS)
California
$423K +$111K +2,182 +36%
Tudor Investment Corp
65
Tudor Investment Corp
Connecticut
$407K +$203K +3,980 +99%
Fidelity Investments
66
Fidelity Investments
Massachusetts
$377K -$3.98K -78 -1%
Los Angeles Capital Management
67
Los Angeles Capital Management
California
$347K +$79.1K +1,550 +30%
RhumbLine Advisers
68
RhumbLine Advisers
Massachusetts
$336K -$3.37K -66 -1%
Jane Street
69
Jane Street
New York
$331K +$281K +5,504 +559%
VRS
70
Virginia Retirement Systems
Virginia
$310K +$239K +4,680 +333%
UBS AM
71
UBS AM
Illinois
$282K +$36.9K +724 +15%
AG
72
Algert Global
California
$281K -$45.2K -886 -14%
GCP
73
GSA Capital Partners
United Kingdom
$279K +$279K +5,477 New
NYLIM
74
New York Life Investment Management
New York
$262K +$29.5K +578 +13%
CANY
75
Caxton Associates (New York)
New York
$258K +$13.7K +268 +6%
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