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Karyopharm Therapeutics
KPTI

Overview Fund Activity

139 hedge funds and large institutions have $499M invested in Karyopharm Therapeutics in 2022 Q1 according to their latest regulatory filings, with 26 funds opening new positions, 42 increasing their positions, 46 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
139
Holders Change
-4
Holders Change %
-2.8%
% of All Funds
2.2%
Holding in Top 10
1
Holding in Top 10 Change
+1
Holding in Top 10 Change %
%
% of All Funds
0.02%
New
26
Increased
42
Reduced
46
Closed
28
Calls
$12M
Puts
$4.09M
Net Calls
+$7.88M
Net Calls Change
+$13.6M

Top Buyers

1
State Street
State Street
Massachusetts
+$40.2M
2
CC
Commodore Capital
New York
+$26.2M
3
ITP
Iron Triangle Partners
Connecticut
+$14.7M
4
Morgan Stanley
Morgan Stanley
New York
+$12.9M
5
Bank of America
Bank of America
North Carolina
+$6.35M

Top Sellers

1
Alkeon Capital Management
Alkeon Capital Management
New York
-$12.6M
2
BlackRock
BlackRock
New York
-$7.3M
3
LOAMS
Lombard Odier Asset Management (Switzerland)
Switzerland
-$6.5M
4
FCM
Frontier Capital Management
Massachusetts
-$2.99M
5
CSS
Cubist Systematic Strategies
Connecticut
-$2.96M
Name Holding Trade Value Shares
Change 		Shares
Change %
Barclays
51
Barclays
United Kingdom
$646K -$693K -6,269 -52%
Walleye Capital
52
Walleye Capital
New York
$612K +$510K +4,612 +498%
RhumbLine Advisers
53
RhumbLine Advisers
Massachusetts
$583K -$115K -1,039 -16%
SFI
54
Susquehanna Fundamental Investments
Pennsylvania
$461K – – –
UBS AM
55
UBS AM
Illinois
$458K -$218K -1,974 -32%
Russell Investments Group
56
Russell Investments Group
United Kingdom
$447K +$442K +4,003 +8,517%
CAM
57
ClariVest Asset Management
California
$440K +$440K +3,973 New
IA
58
IndexIQ Advisors
New York
$394K +$394K +3,563 New
QT
59
Quantbot Technologies
New York
$392K +$347K +3,146 +773%
State Board of Administration of Florida Retirement System
60
State Board of Administration of Florida Retirement System
Florida
$391K – – –
New York State Common Retirement Fund
61
New York State Common Retirement Fund
New York
$386K +$72.3K +655 +23%
AWA
62
Aaron Wealth Advisors
Illinois
$385K +$385K +189 New
Allspring Global Investments
63
Allspring Global Investments
North Carolina
$359K +$74.9K +678 +26%
Capital Fund Management (CFM)
64
Capital Fund Management (CFM)
France
$325K +$325K +2,944 New
Ensign Peak Advisors
65
Ensign Peak Advisors
Utah
$320K – – –
GSEP
66
Golden State Equity Partners
California
$308K – – –
MIM
67
MetLife Investment Management
New Jersey
$308K +$109K +985 +55%
GC
68
GFG Capital
Florida
$305K – – –
Wells Fargo
69
Wells Fargo
California
$302K -$185K -1,666 -38%
EFM
70
E Fund Management
China
$299K +$208K +1,879 +227%
AIG
71
American International Group
New York
$263K -$18.5K -168 -7%
D.E. Shaw & Co
72
D.E. Shaw & Co
New York
$251K -$1.04M -9,463 -81%
Legal & General Group
73
Legal & General Group
United Kingdom
$234K – – –
Invesco
74
Invesco
Georgia
$232K -$221 -2 -0.1%
VOYA Investment Management
75
VOYA Investment Management
Georgia
$227K +$14.1K +127 +7%
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