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Karyopharm Therapeutics
KPTI

Overview Fund Activity

153 hedge funds and large institutions have $608M invested in Karyopharm Therapeutics in 2021 Q2 according to their latest regulatory filings, with 21 funds opening new positions, 54 increasing their positions, 56 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
153
Holders Change
-18
Holders Change %
-10.53%
% of All Funds
2.67%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
21
Increased
54
Reduced
56
Closed
38
Calls
$4.62M
Puts
$14.1M
Net Calls
-$9.52M
Net Calls Change
-$8.17M

Top Buyers

1
RCMNY
Rubric Capital Management (New York)
New York
+$43.9M
2
BlackRock
BlackRock
New York
+$10.6M
3
LOAMS
Lombard Odier Asset Management (Switzerland)
Switzerland
+$5.64M
4
State Street
State Street
Massachusetts
+$5M
5
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
+$3.96M

Top Sellers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$14.2M
2
Wellington Management Group
Wellington Management Group
Massachusetts
-$13.6M
3
LCM
Laurion Capital Management
New York
-$9.49M
4
CLOS
Compagnie Lombard Odier SCmA
Switzerland
-$8.73M
5
Two Sigma Investments
Two Sigma Investments
New York
-$6.67M
Name Holding Trade Value Shares
Change 		Shares
Change %
State of Wisconsin Investment Board
51
State of Wisconsin Investment Board
Wisconsin
$985K – – –
UBS AM
52
UBS AM
Illinois
$871K +$297K +1,918 +52%
CS
53
Credit Suisse
Switzerland
$866K -$60.8K -393 -7%
SFI
54
Susquehanna Fundamental Investments
Pennsylvania
$843K +$651K +4,209 +340%
AA
55
AlphaCentric Advisors
Puerto Rico
$841K +$304K +1,966 +57%
Jacobs Levy Equity Management
56
Jacobs Levy Equity Management
New Jersey
$839K +$839K +5,417 New
Tudor Investment Corp
57
Tudor Investment Corp
Connecticut
$834K -$26.8K -173 -3%
JF
58
Jump Financial
Illinois
$725K +$80.3K +519 +12%
LCM
59
Laurion Capital Management
New York
$627K -$9.49M -61,312 -94%
New York State Common Retirement Fund
60
New York State Common Retirement Fund
New York
$612K -$161K -1,039 -21%
Russell Investments Group
61
Russell Investments Group
United Kingdom
$542K +$95.1K +616 +21%
Balyasny Asset Management
62
Balyasny Asset Management
Illinois
$512K -$2.49M -16,102 -83%
VEA
63
Virtus ETF Advisers
New York
$500K +$85.2K +550 +21%
CSS
64
Cubist Systematic Strategies
Connecticut
$485K +$176K +1,135 +57%
Manulife (Manufacturers Life Insurance)
65
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$415K -$6.82K -44 -2%
AG
66
Algert Global
California
$375K +$375K +2,421 New
DekaBank Deutsche Girozentrale
67
DekaBank Deutsche Girozentrale
Germany
$364K – – –
Squarepoint
68
Squarepoint
New York
$355K +$355K +2,294 New
SCA
69
Spearhead Capital Advisors
Florida
$351K +$72.2K +467 +26%
WMSA
70
Weiss Multi-Strategy Advisers
New York
$344K +$12.2K +79 +4%
State Board of Administration of Florida Retirement System
71
State Board of Administration of Florida Retirement System
Florida
$342K +$70.4K +455 +26%
ProShare Advisors
72
ProShare Advisors
Maryland
$332K +$30K +194 +10%
Wells Fargo
73
Wells Fargo
California
$316K -$762K -4,928 -71%
SEI Investments
74
SEI Investments
Pennsylvania
$314K -$25.4K -166 -7%
Vontobel Holding
75
Vontobel Holding
Switzerland
$310K – – –
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3
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