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Karyopharm Therapeutics
KPTI

Overview Fund Activity

118 hedge funds and large institutions have $103M invested in Karyopharm Therapeutics in 2023 Q3 according to their latest regulatory filings, with 16 funds opening new positions, 40 increasing their positions, 29 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
118
Holders Change
-19
Holders Change %
-13.87%
% of All Funds
1.88%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
16
Increased
40
Reduced
29
Closed
35
Calls
$785K
Puts
$182K
Net Calls
+$603K
Net Calls Change
+$232K

Top Buyers

1
Jacobs Levy Equity Management
Jacobs Levy Equity Management
New Jersey
+$2.25M
2
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
+$1.61M
3
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$1.41M
4
Morgan Stanley
Morgan Stanley
New York
+$834K
5
GCP
GSA Capital Partners
United Kingdom
+$762K

Top Sellers

1
OM
Opaleye Management
Massachusetts
-$3.2M
2
Deutsche Bank
Deutsche Bank
Germany
-$2.06M
3
RCMNY
Rubric Capital Management (New York)
New York
-$1.65M
4
ECM
ExodusPoint Capital Management
New York
-$1.32M
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
-$1.26M
Name Holding Trade Value Shares
Change 		Shares
Change %
Renaissance Technologies
26
Renaissance Technologies
New York
$979K +$84.4K +4,200 +9%
Bank of New York Mellon
27
Bank of New York Mellon
New York
$876K -$9.33K -464 -1%
D.E. Shaw & Co
28
D.E. Shaw & Co
New York
$835K +$33.6K +1,673 +4%
BC
29
Birchview Capital
Vermont
$766K +$376K +18,700 +96%
GCP
30
GSA Capital Partners
United Kingdom
$762K +$762K +37,887 New
SCM
31
Silverarc Capital Management
Massachusetts
$753K +$57.6K +2,865 +8%
AQR Capital Management
32
AQR Capital Management
Connecticut
$672K +$453K +22,517 +206%
PL
33
Parkwood LLC
Ohio
$661K – – –
Nuveen Asset Management
34
Nuveen Asset Management
Illinois
$606K -$14.9K -742 -2%
WVP
35
Worth Venture Partners
New Jersey
$598K – – –
IC
36
Ikarian Capital
Texas
$536K – – –
Macquarie Group
37
Macquarie Group
Australia
$509K – – –
Ameriprise
38
Ameriprise
Minnesota
$478K -$4.24K -211 -0.9%
Bank of America
39
Bank of America
North Carolina
$473K +$21.7K +1,079 +5%
XT
40
XTX Topco
Cayman Islands
$415K -$98.9K -4,919 -19%
BCM
41
Bridgeway Capital Management
Texas
$388K +$388K +19,300 New
Fidelity Investments
42
Fidelity Investments
Massachusetts
$357K +$482 +24 +0.1%
Charles Schwab
43
Charles Schwab
California
$347K -$60.9K -3,029 -15%
AllianceBernstein
44
AllianceBernstein
Tennessee
$258K -$55.8K -2,775 -18%
DCM
45
DAFNA Capital Management
California
$258K – – –
AI
46
Atom Investors
Texas
$256K +$8.32K +414 +3%
RhumbLine Advisers
47
RhumbLine Advisers
Massachusetts
$185K +$4.78K +238 +3%
Susquehanna International Group
48
Susquehanna International Group
Pennsylvania
$185K +$65.4K +3,253 +55%
WP
49
Woodline Partners
California
$180K +$180K +8,941 New
JGC
50
J. Goldman & Co
New York
$161K -$562K -27,983 -78%
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