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Karyopharm Therapeutics

129 hedge funds and large institutions have $340M invested in Karyopharm Therapeutics in 2023 Q1 according to their latest regulatory filings, with 18 funds opening new positions, 52 increasing their positions, 30 reducing their positions, and 43 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
129
Holders Change
-25
Holders Change %
-16.23%
% of All Funds
2.06%
Holding in Top 10
1
Holding in Top 10 Change
+1
Holding in Top 10 Change %
%
% of All Funds
0.02%
New
18
Increased
52
Reduced
30
Closed
43
Calls
$1.03M
Puts
$515K
Net Calls
+$519K
Net Calls Change
-$184K
Name Holding Trade Value Shares
Change
Shares
Change %
D.E. Shaw & Co
26
D.E. Shaw & Co
New York
$2.14M +$940K +16,109 +78%
ACM
27
Altium Capital Management
New York
$1.97M +$1.97M +33,719 New
TC
28
Tejara Capital
United Kingdom
$1.95M
Alyeska Investment Group
29
Alyeska Investment Group
Illinois
$1.87M
AAA
30
Affinity Asset Advisors
New York
$1.79M -$779K -13,352 -30%
Bank of New York Mellon
31
Bank of New York Mellon
New York
$1.77M +$84K +1,439 +5%
Two Sigma Advisers
32
Two Sigma Advisers
New York
$1.56M -$1.17M -20,113 -43%
Macquarie Group
33
Macquarie Group
Australia
$1.48M
BNP Paribas Financial Markets
34
BNP Paribas Financial Markets
France
$1.44M -$210K -3,601 -13%
IC
35
Ikarian Capital
Texas
$1.17M +$1.17M +20,000 New
Susquehanna International Group
36
Susquehanna International Group
Pennsylvania
$1.15M +$156K +2,666 +16%
BC
37
Birchview Capital
Vermont
$1.13M
Ameriprise
38
Ameriprise
Minnesota
$1M +$361K +6,191 +56%
AA
39
AlphaCentric Advisors
Puerto Rico
$934K +$934K +16,000 New
CANY
40
Caxton Associates (New York)
New York
$917K +$621K +10,646 +210%
Wellington Management Group
41
Wellington Management Group
Massachusetts
$910K +$21.1K +362 +2%
Swiss National Bank
42
Swiss National Bank
Switzerland
$901K -$107K -1,840 -11%
Charles Schwab
43
Charles Schwab
California
$866K +$61.7K +1,058 +8%
State of Wisconsin Investment Board
44
State of Wisconsin Investment Board
Wisconsin
$768K +$729K +12,492 +1,864%
DCM
45
DAFNA Capital Management
California
$750K
JPMorgan Chase & Co
46
JPMorgan Chase & Co
New York
$742K -$5.03M -86,100 -87%
Connor, Clark & Lunn Investment Management (CC&L)
47
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$729K -$952K -16,322 -57%
AllianceBernstein
48
AllianceBernstein
Tennessee
$692K +$77K +1,320 +13%
Wells Fargo
49
Wells Fargo
California
$652K +$652K +11,168 +139,600%
PA
50
Profund Advisors
Maryland
$652K +$652K +11,168 New