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Karyopharm Therapeutics
KPTI

Overview Fund Activity

85 hedge funds and large institutions have $285M invested in Karyopharm Therapeutics in 2015 Q4 according to their latest regulatory filings, with 10 funds opening new positions, 37 increasing their positions, 22 reducing their positions, and 14 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
85
Holders Change
-4
Holders Change %
-4.49%
% of All Funds
2.23%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
10
Increased
37
Reduced
22
Closed
14
Calls
$2.38M
Puts
$1.91M
Net Calls
+$474K
Net Calls Change
-$7.02M

Top Buyers

1
Millennium Management
Millennium Management
New York
+$3.56M
2
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$1.81M
3
Wells Fargo
Wells Fargo
California
+$1.64M
4
CS
Credit Suisse
Switzerland
+$630K
5
OPPM
Opus Point Partners Management
New York
+$600K

Top Sellers

1
SAM
Sectoral Asset Management
Quebec, Canada
-$7.51M
2
Citadel Advisors
Citadel Advisors
Florida
-$7.36M
3
Franklin Resources
Franklin Resources
California
-$5.91M
4
TCM
Tekla Capital Management
Massachusetts
-$5.55M
5
CAM
Cormorant Asset Management
Massachusetts
-$3.17M
Name Holding Trade Value Shares
Change 		Shares
Change %
TCIM
26
TIAA CREF Investment Management
New York
$1.01M – – –
Bank of America
27
Bank of America
North Carolina
$967K -$50.3K -253 -5%
OPPM
28
Opus Point Partners Management
New York
$795K +$600K +3,017 +307%
Charles Schwab
29
Charles Schwab
California
$776K +$18.1K +91 +2%
D.E. Shaw & Co
30
D.E. Shaw & Co
New York
$632K -$13.3K -67 -2%
CS
31
Credit Suisse
Switzerland
$630K +$630K +3,172 New
AA
32
ALPS Advisors
Colorado
$624K -$117K -587 -16%
TG
33
TCW Group
California
$596K +$33.2K +167 +6%
California State Teachers Retirement System (CalSTRS)
34
California State Teachers Retirement System (CalSTRS)
California
$568K +$9.95K +50 +2%
Royal Bank of Canada
35
Royal Bank of Canada
Ontario, Canada
$549K +$520K +2,620 +1,807%
Connor, Clark & Lunn Investment Management (CC&L)
36
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$545K +$13.5K +68 +3%
TI
37
Trexquant Investment
Connecticut
$529K +$529K +2,660 New
LCM
38
Landscape Capital Management
New Jersey
$512K +$512K +2,577 New
TA
39
Teachers Advisors
New York
$484K +$37.2K +187 +8%
HCM
40
Highbridge Capital Management
New York
$470K +$25K +126 +6%
AllianceBernstein
41
AllianceBernstein
Tennessee
$427K -$63.4K -319 -13%
ProShare Advisors
42
ProShare Advisors
Maryland
$425K +$35.2K +177 +9%
Susquehanna International Group
43
Susquehanna International Group
Pennsylvania
$420K -$477K -2,401 -53%
TAM
44
Tocqueville Asset Management
New York
$398K – – –
Swiss National Bank
45
Swiss National Bank
Switzerland
$370K – – –
OAM
46
Oxford Asset Management
United Kingdom
$333K +$333K +1,666 New
Group One Trading
47
Group One Trading
Illinois
$305K +$187K +939 +158%
Citadel Advisors
48
Citadel Advisors
Florida
$303K -$7.36M -37,039 -96%
RhumbLine Advisers
49
RhumbLine Advisers
Massachusetts
$295K +$19.9K +100 +7%
Morgan Stanley
50
Morgan Stanley
New York
$257K -$1.51M -7,604 -85%
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