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Karyopharm Therapeutics
KPTI

Overview Fund Activity

78 hedge funds and large institutions have $704M invested in Karyopharm Therapeutics in 2014 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 30 increasing their positions, 18 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
78
Holders Change
+18
Holders Change %
+30%
% of All Funds
2.24%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.06%
New
29
Increased
30
Reduced
18
Closed
10
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
Franklin Resources
Franklin Resources
California
+$104M
2
Fidelity Investments
Fidelity Investments
Massachusetts
+$49.7M
3
PHS
PFM Health Sciences
California
+$16.4M
4
SAM
Sectoral Asset Management
Quebec, Canada
+$12.5M
5
Vanguard Group
Vanguard Group
Pennsylvania
+$7.11M

Top Sellers

1
FCMI
Foresite Capital Management I
California
-$9.7M
2
Wellington Management Group
Wellington Management Group
Massachusetts
-$2.08M
3
Principal Financial Group
Principal Financial Group
Iowa
-$1.98M
4
EI
EAM Investors
California
-$1.97M
5
EAM
Eventide Asset Management
Massachusetts
-$1.76M
Name Holding Trade Value Shares
Change 		Shares
Change %
GPP
26
Great Point Partners
Connecticut
$3.49M +$3.49M +5,000 New
TA
27
Teachers Advisors
New York
$3M +$2.48M +3,554 +475%
BIM
28
BlackRock Investment Management
Delaware
$2.93M +$1.88M +2,696 +180%
JPMorgan Chase & Co
29
JPMorgan Chase & Co
New York
$2.48M -$844K -1,208 -25%
Geode Capital Management
30
Geode Capital Management
Massachusetts
$2.24M +$168K +240 +8%
Bank of New York Mellon
31
Bank of New York Mellon
New York
$2.21M -$341K -489 -13%
TCIM
32
TIAA CREF Investment Management
New York
$2.21M +$823K +1,178 +59%
PA
33
Perceptive Advisors
New York
$2.13M +$2.13M +3,043 New
Morgan Stanley
34
Morgan Stanley
New York
$2.11M +$1.4M +2,003 +198%
MOACM
35
Mutual of America Capital Management
New York
$1.86M -$113K -162 -6%
Millennium Management
36
Millennium Management
New York
$1.49M +$1.49M +2,127 New
SIM
37
Spark Investment Management
New York
$1.48M +$689K +987 +87%
EAM
38
Eventide Asset Management
Massachusetts
$1.4M -$1.76M -2,520 -56%
OM
39
Opaleye Management
Massachusetts
$1.4M +$1.4M +2,000 New
ARC
40
Absolute Return Capital
Massachusetts
$1.27M -$462K -662 -27%
PIM
41
Partner Investment Management
California
$1.16M +$594K +851 +105%
Charles Schwab
42
Charles Schwab
California
$1.12M +$316K +452 +39%
California State Teachers Retirement System (CalSTRS)
43
California State Teachers Retirement System (CalSTRS)
California
$1.05M +$391K +560 +59%
LCM
44
Laurion Capital Management
New York
$847K +$847K +1,213 New
Royal Bank of Canada
45
Royal Bank of Canada
Ontario, Canada
$824K +$824K +1,180 New
Bank of America
46
Bank of America
North Carolina
$741K -$373K -534 -33%
Tudor Investment Corp
47
Tudor Investment Corp
Connecticut
$698K +$698K +1,000 New
Jane Street
48
Jane Street
New York
$658K +$658K +942 New
Swiss National Bank
49
Swiss National Bank
Switzerland
$573K +$573K +820 New
Nuveen Asset Management
50
Nuveen Asset Management
Illinois
$506K +$20.9K +30 +4%
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