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Spyre Therapeutics

85 hedge funds and large institutions have $189M invested in Spyre Therapeutics in 2021 Q4 according to their latest regulatory filings, with 18 funds opening new positions, 26 increasing their positions, 22 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
85
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$263K
Puts
$248K
Net Calls
Net Calls Change

Top Buyers

1 +$6.16M
2 +$4.01M
3 +$1.96M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$946K
5
CAM
ClariVest Asset Management
California
+$832K

Top Sellers

1 -$11.9M
2 -$5.03M
3 -$1.64M
4
ACM
Altium Capital Management
New York
-$1.5M
5
Marshall Wace
Marshall Wace
United Kingdom
-$1.3M
Name Holding Trade Value Shares
Change
Change in
Stake
51
$170K
52
$154K
53
$147K
54
$122K
55
$119K
56
$117K
57
$102K
58
$101K
59
$101K
60
$99K
61
$81K
62
$75K
63
$73K
64
$71K
65
$61K
66
$58K
67
$57K
68
$56K
69
$53K
70
$52K
71
$48K
72
$39K
73
$25K
74
$24K
75
$18K