Citigroup’s Spyre Therapeutics SYRE Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2026
Q2
$7.33M Buy
82,593
+70,587
+588% +$5.15M ﹤0.01% 1836
2026
Q1
$606K Sell
12,006
-88,052
-88% -$3.32M ﹤0.01% 3438
2025
Q4
$3.28M Buy
100,058
+67,162
+204% +$1.75M ﹤0.01% 2318
2025
Q3
$551K Buy
32,896
+3,635
+12% +$59.3K ﹤0.01% 3525
2025
Q2
$438K Sell
29,261
-54,203
-65% -$802K ﹤0.01% 3709
2025
Q1
$1.35M Buy
83,464
+9,712
+13% +$202K ﹤0.01% 3038
2024
Q4
$1.72M Buy
73,752
+48,561
+193% +$1.42M ﹤0.01% 2938
2024
Q3
$741K Buy
25,191
+5,871
+30% +$163K ﹤0.01% 3482
2024
Q2
$454K Sell
19,320
-12,437
-39% -$420K ﹤0.01% 3459
2024
Q1
$1.2M Buy
31,757
+21,460
+208% +$622K ﹤0.01% 2879
2023
Q4
$222K Buy
+10,297
New +$142K ﹤0.01% 3864
2022
Q4
Sell
-25
Closed 5950
2022
Q3
$0 Sell
25
-182
-88% -$2.25K ﹤0.01% 6305
2022
Q2
$3K Buy
207
+34
+20% +$1.19K ﹤0.01% 5800
2022
Q1
$10K Sell
173
-303
-64% -$25.4K ﹤0.01% 5549
2021
Q4
$56K Buy
476
+191
+67% +$30.1K ﹤0.01% 5005
2021
Q3
$57K Buy
285
+86
+43% +$15K ﹤0.01% 4672
2021
Q2
$35K Buy
199
+35
+21% +$6.36K ﹤0.01% 4990
2021
Q1
$33K Sell
164
-239
-59% -$45.9K ﹤0.01% 4950
2020
Q4
$79K Buy
403
+209
+108% +$43.3K ﹤0.01% 5728
2020
Q3
$34K Sell
194
-153
-44% -$28.3K ﹤0.01% 5855
2020
Q2
$80K Sell
347
-27
-7% -$5.14K ﹤0.01% 5761
2020
Q1
$44K Buy
374
+70
+23% +$11.9K ﹤0.01% 6087
2019
Q4
$58K Buy
304
+199
+190% +$39.1K ﹤0.01% 6194
2019
Q3
$20K Sell
105
-193
-65% -$37.6K ﹤0.01% 6741
2019
Q2
$51K Buy
298
+70
+31% +$12.1K ﹤0.01% 6461
2019
Q1
$46K Buy
228
+60
+36% +$12.5K ﹤0.01% 6411
2018
Q4
$32K Sell
168
-11
-6% -$2.33K ﹤0.01% 6582
2018
Q3
$43K Buy
179
+85
+90% +$19.9K ﹤0.01% 6646
2018
Q2
$25K Buy
+94
New +$23.1K ﹤0.01% 6810

Other funds holding SYRE

Citigroup's SYRE Position: Q2 2026 in Review

Citigroup increased its Spyre Therapeutics (SYRE) stake by 588% in Q2 2026, buying an estimated $5.15M and bringing the position to 82,593 shares worth $7.33M. The position accounts for ﹤0.01% of the portfolio, ranked #1836.

Citigroup first reported a position in SYRE in Q2 2018 and has held it in 29 quarters since. 265 funds tracked by Wall St. Rank hold SYRE as of Q2 2026.

  • Citigroup held 82,593 shares of Spyre Therapeutics worth $7.33M as of Q2 2026.
  • Citigroup bought 70,587 Spyre Therapeutics shares in Q2 2026, an estimated $5.15M.
  • Spyre Therapeutics made up ﹤0.01% of Citigroup's portfolio in Q2 2026, its #1836 holding.
  • Citigroup first reported a position in Spyre Therapeutics in Q2 2018 and has held it in 29 quarters since.
  • 265 funds tracked by Wall St. Rank held Spyre Therapeutics as of Q2 2026.

Based on Citigroup's 13F filing for Q2 2026, filed 3 Aug 2026.