VOYA Investment Management
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VOYA Investment Management’s Spyre Therapeutics SYRE Stock Holding History

VOYA Investment Management’s Portfolio SYRE Stock Details SYRE Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$38.3M Buy
431,694
+377,724
+700% +$27.6M 0.03% 369
2026
Q1 		$2.72M Buy
53,970
+26,693
+98% +$1.01M ﹤0.01% 1054
2025
Q4 		$894K Buy
+27,277
New +$713K ﹤0.01% 1515
2025
Q3 		– Sell
-13,589
Closed -$203K – 2639
2025
Q2 		$203K Buy
13,589
+3,241
+31% +$48K ﹤0.01% 2321
2025
Q1 		$167K Sell
10,348
-147
-1% -$3.06K ﹤0.01% 2323
2024
Q4 		$244K Sell
10,495
-856
-8% -$25.1K ﹤0.01% 2301
2024
Q3 		$334K Sell
11,351
-256
-2% -$7.13K ﹤0.01% 2212
2024
Q2 		$273K Buy
+11,607
New +$392K ﹤0.01% 2298
2022
Q2 		– Sell
-619
Closed -$36K – 2886
2022
Q1 		$36K Hold
619
– – ﹤0.01% 2618
2021
Q4 		$73K Sell
619
-176
-22% -$27.8K ﹤0.01% 2708
2021
Q3 		$158K Hold
795
– – ﹤0.01% 2637
2021
Q2 		$138K Sell
795
-65
-8% -$11.8K ﹤0.01% 2697
2021
Q1 		$170K Buy
860
+150
+21% +$28.8K ﹤0.01% 2579
2020
Q4 		$140K Buy
710
+97
+16% +$20.1K ﹤0.01% 2503
2020
Q3 		$109K Hold
613
– – ﹤0.01% 2323
2020
Q2 		$142K Buy
613
+65
+12% +$12.4K ﹤0.01% 2266
2020
Q1 		$64K Hold
548
– – ﹤0.01% 2446
2019
Q4 		$105K Buy
+548
New +$108K ﹤0.01% 2536

Other funds holding SYRE

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
PA
Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return
RI
RTW Investments New York $11.7B AUM 174.13% 1-Year Est. Return
PBA
Paradigm Biocapital Advisors New York $5.34B AUM 380.18% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
VA
VR Adviser New York $3.3B AUM 525.74% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $999B AUM 46.22% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return

VOYA Investment Management's SYRE Position: Q2 2026 in Review

VOYA Investment Management increased its Spyre Therapeutics (SYRE) stake by 700% in Q2 2026, buying an estimated $27.6M and bringing the position to 431,694 shares worth $38.3M. The position accounts for 0.03% of the portfolio, ranked #369.

VOYA Investment Management first reported a position in SYRE in Q4 2019 and has held it in 18 quarters since. 265 funds tracked by Wall St. Rank hold SYRE as of Q2 2026.

  • VOYA Investment Management held 431,694 shares of Spyre Therapeutics worth $38.3M as of Q2 2026.
  • VOYA Investment Management bought 377,724 Spyre Therapeutics shares in Q2 2026, an estimated $27.6M.
  • Spyre Therapeutics made up 0.03% of VOYA Investment Management's portfolio in Q2 2026, its #369 holding.
  • VOYA Investment Management first reported a position in Spyre Therapeutics in Q4 2019 and has held it in 18 quarters since.
  • 265 funds tracked by Wall St. Rank held Spyre Therapeutics as of Q2 2026.

Based on VOYA Investment Management's 13F filing for Q2 2026, filed 12 Aug 2026.