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Spyre Therapeutics

84 hedge funds and large institutions have $328M invested in Spyre Therapeutics in 2021 Q1 according to their latest regulatory filings, with 3 funds opening new positions, 23 increasing their positions, 32 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
84
Holders Change
-8
Holders Change %
-8.7%
% of All Funds
1.48%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.05%
New
3
Increased
23
Reduced
32
Closed
11
Calls
$340K
Puts
$119K
Net Calls
+$221K
Net Calls Change
+$770K
Name Holding Trade Value Shares
Change
Shares
Change %
Two Sigma Advisers
51
Two Sigma Advisers
New York
$268K -$235K -1,184 -47%
New York State Common Retirement Fund
52
New York State Common Retirement Fund
New York
$246K
Deutsche Bank
53
Deutsche Bank
Germany
$243K -$21.7K -110 -8%
JPMorgan Chase & Co
54
JPMorgan Chase & Co
New York
$230K -$4.76K -24 -2%
Manulife (Manufacturers Life Insurance)
55
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$230K -$198 -1 -0.1%
PPA
56
Parametric Portfolio Associates
Washington
$211K +$1.19K +6 +0.6%
AllianceBernstein
57
AllianceBernstein
Tennessee
$185K -$3.95K -20 -2%
VOYA Investment Management
58
VOYA Investment Management
Georgia
$170K +$29.7K +150 +21%
AA
59
AlphaCentric Advisors
Puerto Rico
$166K +$134K +680 +425%
MIM
60
MetLife Investment Management
New Jersey
$161K +$97.3K +491 +153%
ProShare Advisors
61
ProShare Advisors
Maryland
$148K +$10.3K +52 +7%
Two Sigma Investments
62
Two Sigma Investments
New York
$145K -$364K -1,838 -71%
CSS
63
Cubist Systematic Strategies
Connecticut
$141K +$68.2K +345 +94%
MLICM
64
Metropolitan Life Insurance Company (MetLife)
New York
$95.3K -$14K -71 -13%
Wells Fargo
65
Wells Fargo
California
$94K -$208K -1,049 -69%
PCS
66
Personal CFO Solutions
New Jersey
$90K
EGM
67
Engineers Gate Manager
New York
$86K +$86K +432 New
Renaissance Technologies
68
Renaissance Technologies
New York
$83K -$306K -1,548 -79%
BNP Paribas Financial Markets
69
BNP Paribas Financial Markets
France
$55.1K -$14.7K -74 -21%
Legal & General Group
70
Legal & General Group
United Kingdom
$38K -$796 -4 -2%
Citigroup
71
Citigroup
New York
$33K -$48.1K -239 -59%
Royal Bank of Canada
72
Royal Bank of Canada
Ontario, Canada
$32K +$16.8K +83 +111%
Bank of Montreal
73
Bank of Montreal
Ontario, Canada
$29K -$44.4K -228 -60%
AIP
74
Ameritas Investment Partners
Nebraska
$29K
IA
75
IFP Advisors
Florida
$28K +$8.06K +40 +40%