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Spyre Therapeutics
SYRE

Overview Fund Activity

70 hedge funds and large institutions have $95.8M invested in Spyre Therapeutics in 2020 Q1 according to their latest regulatory filings, with 9 funds opening new positions, 23 increasing their positions, 22 reducing their positions, and 6 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
70
Holders Change
+2
Holders Change %
+2.94%
% of All Funds
1.55%
Holding in Top 10
2
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-50%
% of All Funds
0.04%
New
9
Increased
23
Reduced
22
Closed
6
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
AG
Artal Group
Luxembourg
+$466K
2
SCM
Soleus Capital Management
Connecticut
+$365K
3
Jacobs Levy Equity Management
Jacobs Levy Equity Management
New Jersey
+$186K
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$127K
5
Renaissance Technologies
Renaissance Technologies
New York
+$111K

Top Sellers

1
Russell Investments Group
Russell Investments Group
United Kingdom
-$417K
2
Man Group
Man Group
United Kingdom
-$315K
3
State of Wisconsin Investment Board
State of Wisconsin Investment Board
Wisconsin
-$303K
4
PAWC
P.A.W. Capital
Connecticut
-$285K
5
Morgan Stanley
Morgan Stanley
New York
-$152K
Name Holding Trade Value Shares
Change 		Shares
Change %
Charles Schwab
26
Charles Schwab
California
$283K +$4.32K +37 +2%
SCA
27
Snowden Capital Advisors
New York
$240K +$1.4K +12 +0.6%
Deutsche Bank
28
Deutsche Bank
Germany
$238K -$59.6K -511 -20%
UBS Group
29
UBS Group
Switzerland
$205K -$51.1K -439 -20%
California Public Employees Retirement System
30
California Public Employees Retirement System
California
$191K – – –
California State Teachers Retirement System (CalSTRS)
31
California State Teachers Retirement System (CalSTRS)
California
$190K +$2.22K +19 +1%
Jacobs Levy Equity Management
32
Jacobs Levy Equity Management
New Jersey
$186K +$186K +1,596 New
PAWC
33
P.A.W. Capital
Connecticut
$182K -$285K -2,440 -61%
RhumbLine Advisers
34
RhumbLine Advisers
Massachusetts
$177K +$2.22K +19 +1%
Two Sigma Investments
35
Two Sigma Investments
New York
$165K -$66.1K -568 -29%
FSA
36
Franklin Street Advisors
North Carolina
$163K +$23.3K +200 +17%
Two Sigma Advisers
37
Two Sigma Advisers
New York
$154K +$931 +8 +0.6%
JPMorgan Chase & Co
38
JPMorgan Chase & Co
New York
$152K -$73.2K -630 -33%
Prudential Financial
39
Prudential Financial
New Jersey
$142K -$14.9K -128 -9%
William Blair & Company
40
William Blair & Company
Illinois
$127K – – –
D.E. Shaw & Co
41
D.E. Shaw & Co
New York
$127K +$127K +1,090 New
Squarepoint
42
Squarepoint
New York
$111K -$114K -978 -51%
Citadel Advisors
43
Citadel Advisors
Florida
$110K +$42.7K +368 +63%
LF
44
Lee Financial
Texas
$104K – – –
New York State Common Retirement Fund
45
New York State Common Retirement Fund
New York
$88K – – –
Manulife (Manufacturers Life Insurance)
46
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$87K +$5.5K +47 +7%
AIG
47
American International Group
New York
$72K -$4.07K -35 -5%
Susquehanna International Group
48
Susquehanna International Group
Pennsylvania
$70K +$70K +601 New
Millennium Management
49
Millennium Management
New York
$65K +$65K +557 New
VOYA Investment Management
50
VOYA Investment Management
Georgia
$64K – – –
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