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Spyre Therapeutics
SYRE

Overview Fund Activity

66 hedge funds and large institutions have $25.4M invested in Spyre Therapeutics in 2022 Q2 according to their latest regulatory filings, with 13 funds opening new positions, 21 increasing their positions, 17 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
66
Holders Change
-17
Holders Change %
-20.48%
% of All Funds
1.12%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.02%
New
13
Increased
21
Reduced
17
Closed
28
Calls
$23K
Puts
–
Net Calls
+$23K
Net Calls Change
+$20K

Top Buyers

1
SCM
1
Sio Capital Management
New York
$2.36M
2
GPP
2
Great Point Partners
Connecticut
$1.26M
3
BCLSI
3
Bain Capital Life Sciences Investors
Massachusetts
$2.7M
4
PAMS
4
Pictet Asset Management (Switzerland)
Switzerland
$2.47M
5
Adage Capital Partners
5
Adage Capital Partners
Massachusetts
$758K

Top Sellers

1
LCM
1
Laurion Capital Management
New York
$0
2
Deutsche Bank
2
Deutsche Bank
Germany
$0
3
Jacobs Levy Equity Management
3
Jacobs Levy Equity Management
New Jersey
$0
4
BlackRock
4
BlackRock
New York
$540K
5
Nuveen Asset Management
5
Nuveen Asset Management
Illinois
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
Bank of America
51
Bank of America
North Carolina
$4K -$5.86K -428 -59%
Citigroup
52
Citigroup
New York
$3K +$493 +34 +20%
BNP Paribas Financial Markets
53
BNP Paribas Financial Markets
France
$2.66K +$858 +68 +48%
Legal & General Group
54
Legal & General Group
United Kingdom
$2K – – –
Group One Trading
55
Group One Trading
Illinois
$2K +$65 +4 +3%
JPMorgan Chase & Co
56
JPMorgan Chase & Co
New York
$1K -$9.72K -904 -91%
Wells Fargo
57
Wells Fargo
California
$1K -$1.87K -183 -65%
Fidelity Investments
58
Fidelity Investments
Massachusetts
$1K +$917 +55 +1,100%
Federated Hermes
59
Federated Hermes
Pennsylvania
$1K +$1K +77 New
O
60
OrbiMed
New York
$908 -$586 -46,356 -39%
LCM
61
Laurion Capital Management
New York
– -$3.62M -63,026 Closed
Deutsche Bank
62
Deutsche Bank
Germany
– -$1.19M -20,605 Closed
Jacobs Levy Equity Management
63
Jacobs Levy Equity Management
New Jersey
– -$1M -17,447 Closed
CAM
64
ClariVest Asset Management
California
– -$424K -7,365 Closed
Nuveen Asset Management
65
Nuveen Asset Management
Illinois
– -$425K -6,765 Closed
Marshall Wace
66
Marshall Wace
United Kingdom
– -$355K -6,167 Closed
Walleye Capital
67
Walleye Capital
New York
– -$312K -5,424 Closed
Charles Schwab
68
Charles Schwab
California
– -$246K -4,272 Closed
AG
69
Algert Global
California
– -$131K -2,278 Closed
AA
70
ALPS Advisors
Colorado
– -$117K -2,029 Closed
RhumbLine Advisers
71
RhumbLine Advisers
Massachusetts
– -$113K -1,957 Closed
AQR Capital Management
72
AQR Capital Management
Connecticut
– -$85K -1,471 Closed
AllianceBernstein
73
AllianceBernstein
Tennessee
– -$50K -864 Closed
AIG
74
American International Group
New York
– -$46K -803 Closed
California State Teachers Retirement System (CalSTRS)
75
California State Teachers Retirement System (CalSTRS)
California
– -$40K -688 Closed
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