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Spyre Therapeutics
SYRE

Overview Fund Activity

78 hedge funds and large institutions have $286M invested in Spyre Therapeutics in 2021 Q2 according to their latest regulatory filings, with 3 funds opening new positions, 29 increasing their positions, 26 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
78
Holders Change
-6
Holders Change %
-7.14%
% of All Funds
1.36%
Holding in Top 10
3
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.05%
New
3
Increased
29
Reduced
26
Closed
9
Calls
$316K
Puts
$104K
Net Calls
+$212K
Net Calls Change
-$9K

Top Buyers

1
SCM
1
Suvretta Capital Management
New York
$14.6M
2
GPP
2
Great Point Partners
Connecticut
$6.26M
3
ACM
3
Altium Capital Management
New York
$4.24M
4
Millennium Management
4
Millennium Management
New York
$3.78M
5
Assenagon Asset Management
5
Assenagon Asset Management
Luxembourg
$1.96M

Top Sellers

1
Point72 Asset Management
1
Point72 Asset Management
Connecticut
$3.27M
2
Marshall Wace
2
Marshall Wace
United Kingdom
$4.53M
3
BlackRock
3
BlackRock
New York
$21.6M
4
DCM
4
Driehaus Capital Management
Illinois
$0
5
Jacobs Levy Equity Management
5
Jacobs Levy Equity Management
New Jersey
$413K
Name Holding Trade Value Shares
Change 		Shares
Change %
Manulife (Manufacturers Life Insurance)
51
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$185K -$18K -103 -9%
AllianceBernstein
52
AllianceBernstein
Tennessee
$178K +$15.3K +88 +9%
Deutsche Bank
53
Deutsche Bank
Germany
$167K -$46.8K -269 -22%
Russell Investments Group
54
Russell Investments Group
United Kingdom
$165K -$415K -2,418 -72%
California Public Employees Retirement System
55
California Public Employees Retirement System
California
$145K -$448K -2,578 -76%
Bank of America
56
Bank of America
North Carolina
$141K -$136K -779 -49%
VOYA Investment Management
57
VOYA Investment Management
Georgia
$138K -$11.3K -65 -8%
ProShare Advisors
58
ProShare Advisors
Maryland
$134K +$4.17K +24 +3%
Cerity Partners
59
Cerity Partners
New York
$125K +$125K +720 New
Invesco
60
Invesco
Georgia
$90K +$90K +522 New
CSS
61
Cubist Systematic Strategies
Connecticut
$82K -$42.7K -244 -34%
PCS
62
Personal CFO Solutions
New Jersey
$79K – – –
Barclays
63
Barclays
United Kingdom
$40K -$227K -1,291 -85%
Citigroup
64
Citigroup
New York
$35K +$6.16K +35 +21%
BNP Paribas Financial Markets
65
BNP Paribas Financial Markets
France
$32.7K -$15.7K -90 -32%
IA
66
IFP Advisors
Florida
$27K +$3.4K +20 +14%
AIP
67
Ameritas Investment Partners
Nebraska
$26K – – –
Legal & General Group
68
Legal & General Group
United Kingdom
$23K -$10.5K -60 -31%
TRCT
69
Tower Research Capital (TRC)
New York
$21K +$2.6K +15 +14%
Royal Bank of Canada
70
Royal Bank of Canada
Ontario, Canada
$20K -$6.56K -39 -25%
Wells Fargo
71
Wells Fargo
California
$16K -$70K -385 -81%
OSAM
72
O'Shaughnessy Asset Management
Connecticut
$12K – – –
QCG
73
Quadrant Capital Group
Ohio
$8K – – –
PCM
74
Penserra Capital Management
California
$7K +$156 +1 +2%
Group One Trading
75
Group One Trading
Illinois
$2K +$667 +4 +50%
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3
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