SYRE icon

Spyre Therapeutics
SYRE

Overview Fund Activity

92 hedge funds and large institutions have $319M invested in Spyre Therapeutics in 2020 Q4 according to their latest regulatory filings, with 10 funds opening new positions, 33 increasing their positions, 29 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
92
Holders Change
-2
Holders Change %
-2.13%
% of All Funds
1.63%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.05%
New
10
Increased
33
Reduced
29
Closed
12
Calls
$2K
Puts
$551K
Net Calls
-$549K
Net Calls Change
-$550K

Top Buyers

1
Point72 Asset Management
Point72 Asset Management
Connecticut
+$23M
2
PAMU
Pictet Asset Management (UK)
United Kingdom
+$10.9M
3
Millennium Management
Millennium Management
New York
+$3.19M
4
SCM
Suvretta Capital Management
New York
+$1.81M
5
BlackRock
BlackRock
New York
+$883K

Top Sellers

1
NCM
Nantahala Capital Management
Connecticut
-$9.04M
2
BBA
Baker Bros. Advisors
New York
-$7.63M
3
OM
Opaleye Management
Massachusetts
-$2.66M
4
Renaissance Technologies
Renaissance Technologies
New York
-$2.34M
5
Jacobs Levy Equity Management
Jacobs Levy Equity Management
New Jersey
-$985K
Name Holding Trade Value Shares
Change 		Shares
Change %
Wells Fargo
51
Wells Fargo
California
$300K +$42.8K +217 +17%
Citadel Advisors
52
Citadel Advisors
Florida
$265K -$108K -552 -29%
Deutsche Bank
53
Deutsche Bank
Germany
$263K -$252K -1,283 -49%
New York State Common Retirement Fund
54
New York State Common Retirement Fund
New York
$245K -$57.5K -292 -19%
JPMorgan Chase & Co
55
JPMorgan Chase & Co
New York
$233K +$110K +558 +89%
Manulife (Manufacturers Life Insurance)
56
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$229K +$26.5K +135 +13%
PPA
57
Parametric Portfolio Associates
Washington
$208K +$9.44K +48 +5%
AllianceBernstein
58
AllianceBernstein
Tennessee
$188K -$22.8K -116 -11%
LF
59
Lee Financial
Texas
$176K – – –
TI
60
Trexquant Investment
Connecticut
$158K +$158K +805 New
VOYA Investment Management
61
VOYA Investment Management
Georgia
$140K +$19.1K +97 +16%
ProShare Advisors
62
ProShare Advisors
Maryland
$137K +$40K +203 +41%
Barclays
63
Barclays
United Kingdom
$116K -$38.6K -196 -25%
MLICM
64
Metropolitan Life Insurance Company (MetLife)
New York
$109K – – –
Bank of America
65
Bank of America
North Carolina
$106K -$282K -1,439 -73%
VF
66
Virtu Financial
New York
$97K +$97K +494 New
CS
67
Credit Suisse
Switzerland
$91K +$91K +464 New
PCS
68
Personal CFO Solutions
New Jersey
$90K +$90K +456 New
Susquehanna International Group
69
Susquehanna International Group
Pennsylvania
$84K -$4.54K -23 -5%
Citigroup
70
Citigroup
New York
$79K +$41K +209 +108%
Principal Financial Group
71
Principal Financial Group
Iowa
$79K +$79K +401 New
Bank of Montreal
72
Bank of Montreal
Ontario, Canada
$74K +$40.2K +205 +119%
CSS
73
Cubist Systematic Strategies
Connecticut
$72K +$2.35K +12 +3%
BNP Paribas Financial Markets
74
BNP Paribas Financial Markets
France
$69.3K -$9.06K -46 -12%
TRCT
75
Tower Research Capital (TRC)
New York
$67K -$215K -1,091 -76%
1 2
3
4 5