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Spyre Therapeutics

87 hedge funds and large institutions have $352M invested in Spyre Therapeutics in 2020 Q2 according to their latest regulatory filings, with 25 funds opening new positions, 43 increasing their positions, 13 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

267% more capital invested

Capital invested by funds: $95.8M → $352M (+$256M)

231% more repeat investments, than reductions

Existing positions increased: 43 | Existing positions reduced: 13

213% more first-time investments, than exits

New positions opened: 25 | Existing positions closed: 8

50% more funds holding in top 10

Funds holding in top 10: 23 (+1)

24% more funds holding

Funds holding: 7087 (+17)

0.58% more ownership

Funds ownership: 2.83%3.41% (+0.58%)

Holders
87
Holders Change
+17
Holders Change %
+24.29%
% of All Funds
1.78%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.06%
New
25
Increased
43
Reduced
13
Closed
8
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
PPA
51
Parametric Portfolio Associates
Washington
$279K +$229K +1,205 New
Citadel Advisors
52
Citadel Advisors
Florida
$261K +$33.9K +178 +19%
AAP
53
Ardsley Advisory Partners
Connecticut
$251K +$206K +1,084 New
AIG
54
American International Group
New York
$238K +$77.5K +407 +66%
Manulife (Manufacturers Life Insurance)
55
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$236K +$54.7K +287 +39%
Morgan Stanley
56
Morgan Stanley
New York
$235K +$168K +881 +638%
Prudential Financial
57
Prudential Financial
New Jersey
$234K -$39.8K -209 -17%
AllianceBernstein
58
AllianceBernstein
Tennessee
$229K +$113K +592 +148%
Barclays
59
Barclays
United Kingdom
$213K +$110K +578 +167%
SG Americas Securities
60
SG Americas Securities
New York
$212K +$95K +499 +120%
LF
61
Lee Financial
Texas
$207K
MIM
62
MetLife Investment Management
New Jersey
$186K +$153K +805 New
Bank of America
63
Bank of America
North Carolina
$179K +$44.9K +236 +44%
Connor, Clark & Lunn Investment Management (CC&L)
64
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$149K +$123K +646 New
VOYA Investment Management
65
VOYA Investment Management
Georgia
$142K +$12.4K +65 +12%
JP Morgan Chase
66
JP Morgan Chase
New York
$131K -$142K -743 -57%
MLICM
67
Metropolitan Life Insurance Company (MetLife)
New York
$129K +$106K +556 New
TI
68
Trexquant Investment
Connecticut
$126K +$104K +547 New
ProShare Advisors
69
ProShare Advisors
Maryland
$119K +$97.7K +513 New
Jane Street
70
Jane Street
New York
$115K +$95K +499 New
TRCT
71
Tower Research Capital (TRC)
New York
$98K +$80.8K +424 New
CSS
72
Cubist Systematic Strategies
Connecticut
$98K +$81.1K +426 New
Citigroup
73
Citigroup
New York
$80K -$5.14K -27 -7%
Legal & General Group
74
Legal & General Group
United Kingdom
$62K +$23.6K +124 +87%
Bank of Montreal
75
Bank of Montreal
Ontario, Canada
$48K +$28.2K +148 +218%

SYRE Hedge Fund Activity: Q2 2020 in Review

87 of the 4,878 institutional investors tracked by Wall St. Rank reported a position in Spyre Therapeutics (SYRE) for Q2 2020, worth a combined $352M — up 267% from $95.8M a quarter earlier.

Buyers outnumbered sellers: 25 funds opened new SYRE positions and 8 closed out — a net gain of 17 holders — while 43 added to existing stakes and 13 trimmed.

The largest buyer was Bain Capital Life Sciences Investors, opening a new position worth an estimated $20.6M. The largest seller was Soleus Capital Management, cutting an estimated $1.27M.

  • 87 institutional investors held Spyre Therapeutics (SYRE) as of Q2 2020, up from 70 in Q1 2020.
  • Funds reported $352M of Spyre Therapeutics stock for Q2 2020, up 267% quarter-over-quarter.
  • 25 funds opened new Spyre Therapeutics positions in Q2 2020 and 8 closed out, a net change of +17 holders.
  • The largest Spyre Therapeutics buyer in Q2 2020 was Bain Capital Life Sciences Investors, an estimated $20.6M added.
  • The largest Spyre Therapeutics seller in Q2 2020 was Soleus Capital Management, an estimated $1.27M sold.

Based on aggregated 13F filings for Q2 2020.