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Spyre Therapeutics

43 hedge funds and large institutions have $31.9M invested in Spyre Therapeutics in 2023 Q2 according to their latest regulatory filings, with 15 funds opening new positions, 4 increasing their positions, 8 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

166% more capital invested

Capital invested by funds: $12M → $31.9M (+$19.9M)

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

1.81% more ownership

Funds ownership: 2.53%4.34% (+1.8%)

6% less first-time investments, than exits

New positions opened: 15 | Existing positions closed: 16

2% less funds holding

Funds holding: 4443 (-1)

50% less repeat investments, than reductions

Existing positions increased: 4 | Existing positions reduced: 8

100% less call options, than puts

Call options by funds: $0 | Put options by funds: $1K

Holders
43
Holders Change
-1
Holders Change %
-2.27%
% of All Funds
0.68%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
15
Increased
4
Reduced
8
Closed
16
Calls
Puts
$1K
Net Calls
-$1K
Net Calls Change
-$1K
Name Holding Trade Value Shares
Change
Change in
Stake
HF
26
HRT Financial
New York
$74K +$31.2K +6,581 New
YF
27
Yu Fan
$50.5K
Northern Trust
28
Northern Trust
Illinois
$44.1K
Jane Street
29
Jane Street
New York
$24.5K +$2.18K +460 +27%
Susquehanna International Group
30
Susquehanna International Group
Pennsylvania
$16.3K +$6.86K +1,447 New
Franklin Resources
31
Franklin Resources
California
$14.1K
Bank of New York Mellon
32
Bank of New York Mellon
New York
$10.5K
TRCT
33
Tower Research Capital (TRC)
New York
$10.3K -$2.77K -585 -39%
Wells Fargo
34
Wells Fargo
California
$3.94K +$100 +21 +6%
UBS Group
35
UBS Group
Switzerland
$3.65K +$1.54K +324 New
Osaic Holdings
36
Osaic Holdings
Arizona
$2.25K +$948 +200 New
Morgan Stanley
37
Morgan Stanley
New York
$1.49K -$1.96K -414 -76%
IA
38
IFP Advisors
Florida
$1.29K
Royal Bank of Canada
39
Royal Bank of Canada
Ontario, Canada
$1K +$251 +53 New
Simplex Trading
40
Simplex Trading
Illinois
$1K +$522 +110 +5,500%
JP Morgan Chase
41
JP Morgan Chase
New York
$481
Group One Trading
42
Group One Trading
Illinois
$258 -$436 -92 -80%
Barclays
43
Barclays
United Kingdom
$45
BCLSI
44
Bain Capital Life Sciences Investors
Massachusetts
-$1.55M -213,908 Closed
SCM
45
Sio Capital Management
New York
-$871K -120,198 Closed
O
46
OrbiMed
New York
-$521K -71,889 Closed
Adage Capital Partners
47
Adage Capital Partners
Massachusetts
-$435K -60,000 Closed
SFM
48
Sphera Funds Management
Israel
-$187K -25,859 Closed
Two Sigma Investments
49
Two Sigma Investments
New York
-$92.9K -12,820 Closed
Assenagon Asset Management
50
Assenagon Asset Management
Luxembourg
-$92.4K -12,738 Closed

SYRE Hedge Fund Activity: Q2 2023 in Review

43 of the 6,369 institutional investors tracked by Wall St. Rank reported a position in Spyre Therapeutics (SYRE) for Q2 2023, worth a combined $31.9M — up 166% from $12M a quarter earlier.

Sellers outnumbered buyers: 16 funds closed out of SYRE and 15 opened new positions — a net loss of 1 holder — while 8 trimmed existing stakes and 4 added.

The largest buyer was Fairmount Funds Management, opening a new position worth an estimated $1.79M. The largest seller was Bain Capital Life Sciences Investors, exiting entirely with an estimated $1.55M sold.

  • 43 institutional investors held Spyre Therapeutics (SYRE) as of Q2 2023, down from 44 in Q1 2023.
  • Funds reported $31.9M of Spyre Therapeutics stock for Q2 2023, up 166% quarter-over-quarter.
  • 15 funds opened new Spyre Therapeutics positions in Q2 2023 and 16 closed out, a net change of -1 holder.
  • The largest Spyre Therapeutics buyer in Q2 2023 was Fairmount Funds Management, an estimated $1.79M added.
  • The largest Spyre Therapeutics seller in Q2 2023 was Bain Capital Life Sciences Investors, an estimated $1.55M sold.

Based on aggregated 13F filings for Q2 2023.